Sébastien BROT

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Publications

Host-to-graft Propagation of α-synuclein in a Mouse Model of Parkinson’s Disease: Intranigral Versus Intrastriatal Transplantation

Maëlig Patrigeon , Sébastien Brot , Marie-Laure Bonnet , Laure Belnoue , Afsaneh Gaillard
Transplantation, 2023, 107 (8), p. 201-212. ⟨10.1097/TP.0000000000004565⟩
Article dans une revue hal-04132835 v1
Image document

Deciphering Brain Metastasis Stem Cell Properties From Colorectal Cancer Highlights Specific Stemness Signature and Shared Molecular Features

Amandine Desette , Pierre-Olivier Guichet , Sheik Emambux , Konstantin Masliantsev , Ulrich Cortes et al.
Cellular and Molecular Gastroenterology and Hepatology, 2023, 16 (5), pp.757-782. ⟨10.1016/j.jcmgh.2023.07.008⟩
Article dans une revue hal-04302791 v1
Image document

Long-Term Evaluation of Intranigral Transplantation of Human iPSC-Derived Dopamine Neurons in a Parkinson’s Disease Mouse Model

Sébastien Brot , Nabila Pyrenina Thamrin , Marie-Laure Bonnet , Maureen Francheteau , Maëlig Patrigeon et al.
Cells, 2022, 11 (10), pp.1596. ⟨10.3390/cells11101596⟩
Article dans une revue hal-03682097 v1

Beneficial Effects of Hyaluronan-Based Hydrogel Implantation after Cortical Traumatic Injury

Anaïs Lainé , Sébastien Brot , Afsaneh Gaillard
Cells, 2022, 11 (23), pp.3831. ⟨10.3390/cells11233831⟩
Article dans une revue hal-04132825 v1
Image document

Better Outcomes with Intranigral versus Intrastriatal Cell Transplantation: Relevance for Parkinson’s Disease

Marine Droguerre , Sébastien Brot , Clément Vitrac , Marianne Benoit-Marand , Laure Belnoue et al.
Cells, 2022, 11 (7), ⟨10.3390/cells11071191⟩
Article dans une revue hal-03637153 v1

Neuroprotective effects of neuropeptide Y against neurodegenerative disease

Stéphanie Pain , Sébastien Brot , Afsaneh Gaillard
Current Neuropharmacology, 2021, 19, ⟨10.2174/1570159X19666210906120302⟩
Article dans une revue hal-03361423 v1

Characterization of Inflammation in Delayed Cortical Transplantation

Nissrine Ballout , Tristan Rochelle , Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau et al.
Frontiers in Molecular Neuroscience, 2019, 12, ⟨10.3389/fnmol.2019.00160⟩
Article dans une revue hal-02498268 v1
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A Delay between Motor Cortex Lesions and Neuronal Transplantation Enhances Graft Integration and Improves Repair and Recovery

Sophie Péron , Marine Droguerre , Franck Debarbieux , Nissrine Ballout , Marianne Benoit-Marand et al.
Journal of Neuroscience, 2017, 37 (7), pp.1820-1834. ⟨10.1523/JNEUROSCI.2936-16.2017⟩
Article dans une revue hal-02500429 v1

Collapsin response-mediator protein 5 (CRMP5) phosphorylation at threonine 516 regulates neurite outgrowth inhibition

Sébastien Brot , Hinda Smaoune , Mina Youssef-Issa , Céline Malleval , Claire Benetollo et al.
European Journal of Neuroscience, 2014, 40 (7), pp.3010-3020. ⟨10.1111/ejn.12674⟩
Article dans une revue istex hal-02511291 v1

Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA

Dominique Bétemps , Jérémy Verchère , Sébastien Brot , Eric Morignat , Luc Bousset et al.
Acta Neuropathologica Communications, 2013, 2, pp.29. ⟨10.1186/2051-5960-2-29⟩
Article dans une revue hal-01183383 v1

Identification of a new CRMP5 isoform present in the nucleus of cancer cells and enhancing their proliferation

Sébastien Brot , Céline Malleval , Claire Benetollo , Carole Auger , David Meyronet et al.
Experimental Cell Research, 2013, 319 (5), pp.588-599. ⟨10.1016/j.yexcr.2012.12.011⟩
Article dans une revue istex hal-02511307 v1

Collapsin Response Mediator Protein 5 (CRMP5) Induces Mitophagy Thereby Regulating Mitochondrion Numbers in Dendrites.

Sébastien Brot , Carole Auger , Rabia Bentata , Véronique Rogemond , Stéphane Ménigoz et al.
Journal of Biological Chemistry, 2013, 289, pp.2261-2276. ⟨10.1074/jbc.M113.490862⟩
Article dans une revue hal-00917349 v1
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CRMP5 Interacts with Tubulin to Inhibit Neurite Outgrowth, Thereby Modulating the Function of CRMP2

Sébastien Brot , Véronique Rogemond , Valérie Perrot , Naura Chounlamountri , Carole Auger et al.
Journal of Neuroscience, 2010, 30 (32), pp.10639-10654. ⟨10.1523/JNEUROSCI.0059-10.2010⟩
Article dans une revue hal-02351827 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot
PHysiopathology Of Parkinson’s disEase » (HOPE), Jan 2020, Paris, France
Communication dans un congrès hal-02511362 v1

La reprogrammation d’hiPSC par ARNm, une nouvelle approche pour la transplantation de neurones dopaminergiques

Sébastien Brot
Journée scientifique SFR FED 4226 Neuroimagerie Fonctionnelle, Jun 2017, Poitiers, France
Communication dans un congrès hal-02511347 v1

Functional integration of intranigral grafted hiPSC derived dopamine neurons in a mouse model of Parkinson disease

Bérangère Ballion , Sébastien Brot , Laure Belnoue , Afsaneh Gaillard
FENS Forum 2022, Jul 2022, Paris, France.
Poster de conférence hal-04517426 v1

Host to graft propagation of alpha-synuclein in Parkinson’s disease: intra-nigral versus intra-striatal transplantation

Maëlig Patrigeon , Sébastien Brot , Marie-Laure Bonnet , Laure Belnoue , Afsaneh Gaillard
13th FENS Forum of Neuroscience, Jul 2022, Paris, France
Poster de conférence hal-05008798 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Bérangère Ballion , Maëlig Patrigeon , Maureen Francheteau et al.
13th FENS Forum of Neuroscience, Jul 2022, Paris, France
Poster de conférence hal-05008791 v1

The potential of motor cortical neurons derived hiPSC transplantation for brain repair following traumatic brain injury

Laure Belnoue , Hammam I. El Hajj , Marie-Laure Bonnet , Sébastien Brot , Afsaneh Gaillard
NeuroFrance 2021, May 2021, Strasbourg, France
Poster de conférence hal-03221118 v1

Host to graft propagation of α-synuclein in Parkinson’s disease: intra-nigral versus intra-striatal transplantation.

Maëlig Patrigeon , Sébastien Brot , Marie-Laure Bonnet , Laure Belnoue , Afsaneh Gaillard
NeuroFrance 2021, May 2021, Strasbourg, France
Poster de conférence hal-03221475 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Bérangère Ballion , Maëlig Patrigeon , Maureen Francheteau et al.
31st Annual meeting of the Network for European CNS Transplantation and Restoration (NECTAR), Nov 2021, Edinburgh, France.
Poster de conférence hal-03637185 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Maëlig Patrigeon , Maureen Francheteau , Laure Belnoue et al.
NeuroFrance 2021, May 2021, Strasbourg, France
Poster de conférence hal-03221124 v1
Image document

Biomaterials to enhance the integration of grafted human iPSC-derived motor cortical neurons in a mice model of traumatic injury

Oriane Rabesandratana , Anaïs Lainé , Marie-Laure Bonnet , Laure Belnoue , Sébastien Brot et al.
FSSCR annual meeting 2021, Nov 2021, Montpellier, France
Poster de conférence hal-03489108 v1

Modelling Parkinson´s disease with patient induced pluripotent stem cells

Nabila Pyrenina Thamrin , Marie-Laure Bonnet , Maëlig Patrigeon , Laure Belnoue , Jean Christophe C Corvol et al.
NeuroFrance 2021, May 2021, Strasbourg, France
Poster de conférence hal-03221486 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Bérangère Ballion , Maëlig Patrigeon , Maureen Francheteau et al.
31st Annual meeting of the Network for European CNS Transplantation and Restoration (NECTAR), Nov 2021, Edinburg, United Kingdom
Poster de conférence hal-05008766 v1

Functional integration of grafted hiPSC derived dopamine neurons in a murine model of Parkinson's disease

Bérangère Ballion , Laure Belnoue , Sébastien Brot , Afsaneh Gaillard
NeuroFrance 2021, May 2021, Strasbourg, France
Poster de conférence hal-03405614 v1

Therapeutic effects of hyaluronan-based hydrogel after cortical traumatic injury

Anaïs Lainé , Sébastien Brot , Oriane Rabesandratana , Afsaneh Gaillard
NeuroFrance 2021, May 2021, Strasbourg, France
Poster de conférence hal-03221468 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Laure Belnoue , Afsaneh Gaillard
PHysiopathology Of Parkinson’s disEase » (HOPE), Jan 2020, Paris, France
Poster de conférence hal-02511393 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard
LE STUDIUM CONFERENCE : Induced Pluripotent Stem Cells (iPSCs): From Disease Models to Mini-Organs, Jan 2019, Tours, France
Poster de conférence hal-02512709 v1

Absence of interleukin 33 impaired axonal outgrowth of grafted cortical neurons.

Anaïs Lainé , Nissrine Ballout , Marie Droguerre , Sébastien Brot , Maureen Francheteau et al.
NeuroFrance, the international conference of the french society of Neuroscience, May 2019, Marseille, France
Poster de conférence hal-02547007 v1

The potential of motor cortical neurons derived hiPSC transplantation for brain repair following traumatic brain injury

Hammam L El Hajj , Laure Belnoue , Marie-Laure Bonnet , Sébastien Brot , Afsaneh Gaillard
Neurofrance, Jun 2019, Marseille, France
Poster de conférence hal-02516060 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard
FSSCR 3rd Annual Meeting, Nov 2019, Lyon, France
Poster de conférence hal-02512692 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard
From 3D culture to organoïds - AVIESAN, Dec 2019, Paris, France
Poster de conférence hal-02512008 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard
11th FENS Forum of Neuroscience, Jul 2018, Berlin, Germany
Poster de conférence hal-02512713 v1

Differentiation of human iPSC into neurons of motor cortex and grafting into injured motor cortex of adult mice

Hammam L El Hajj , Sébastien Brot , Marie-Laure Bonnet , Afsaneh Gaillard
11th FENS forum of Neurosciences, Jul 2018, Berlin, Germany
Poster de conférence hal-02516097 v1

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard
Symposium "(Re)Constructing the nervous system: stem cells and beyond" Institut fer à Moulin, Sep 2017, Paris, France
Poster de conférence hal-02516028 v1

Dopamine neurons derived from human induced pluripotent stem cell reprogrammed by mRNA

Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard
Neurofrane, May 2017, Bordeaux, France
Poster de conférence hal-02516038 v1

Beneficial effects of inflammation in delayed cortical transplantation

Nissrine Ballout , Tristan Rochelle , Sébastien Brot , Maureen Francheteau , Jean-Marc Gombert et al.
Neurofrance, May 2017, Bordeaux, France
Poster de conférence hal-02517467 v1

Molecular and cellular alterations underlying motor disorders in autism spectrum disorders mouse models

Obélia Haida , Tareq Al Sagheer , Anais Balbous , Sébastien Brot , Maureen Francheteau et al.
Séminaire thématique bio-santé ED 524, Mar 2016, Pouligny-Notre-Dame, France
Poster de conférence hal-02556995 v1

Study of Neuroinflammation after cortical lesion and transplantation with or without delay

Nissrine Ballout , Tristan Rochelle , Sébastien Brot , Maureen Francheteau , Jean-Marc Gombert et al.
Plasticité cérébrale, de la recherche fondamentale à la clinique 2e Journées Thématiques de la société des Neurosciences, May 2016, Tours, France
Poster de conférence hal-02517855 v1

Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells

Sandie Brisson , Bhaskar Saha , Tristan Rochelle , Sébastien Brot , Marie-Laure Bonnet et al.
Plasticité cérébrale, de la recherche fondamentale à la clinique - 2e Journées Thématiques de la société des neurosciences, May 2016, Tours, France
Poster de conférence hal-02517846 v1

Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells

Sébastien Brot , Sandie Brisson , Bhaskar Saha , Tristan Rochelle , Marie-Laure Bonnet et al.
3ème Journée Scientifique de la SFR Tours-Poitiers, Jun 2015, Tours, France
Poster de conférence hal-02517803 v1

Study of Neuroinflammation after cortical lesion and transplantation with or without delay

Nissrine Ballout , Tristan Rochelle , Sébastien Brot , Maureen Francheteau , Jean-Marc Gombert et al.
12e colloque de la société des Neurosciences, May 2015, Montpellier, France
Poster de conférence hal-02517504 v1

Delaying cortical transplantation improves the outcome of the graft

Afsaneh Gaillard , Sophie Péron , Marine Droguerre , Nissrine Ballout , Sébastien Brot et al.
9th FENS Forum of Neuroscience, Jul 2014, Milan, Italy
Poster de conférence hal-02517797 v1

Nigrostriatal pathway reconstruction by transplanting embryonic stem cell-derived dopaminergic neurons in Parkinson’s disease

Tristan Rochelle , Sandie Brisson , Sébastien Brot , Marie-Laure Bonnet , Marine Droguerre et al.
2ème Journée Scientifique de la SFR Tours-Poitiers, Jun 2014, Poitiers, France
Poster de conférence hal-02517734 v1

Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells

Sandie Brisson , Bhaskar Saha , Tristan Rochelle , Sébastien Brot , Marie-Laure Bonnet et al.
Journée de recherche Tours-Poitiers-Limoges, Jan 2014, Tours, France
Poster de conférence hal-02517712 v1

Collapsin Response Mediator Protein 5, a multifunction protein involved in neuronal polarity and mitochondrial machinery

Sébastien Brot , Carole Auger , Véronique Rogemond , Jérome Honnorat , Mahnaz Moradi-Améli
7th FENS Forum of European Neuroscience, Jul 2010, Amsterdam, Netherlands
Poster de conférence hal-02518829 v1

Differential localization of CRMP5 in cancer cells compared to normal condition

Sébastien Brot , Claire Benetollo , Celine Malleval , Jérome Honnorat
5ème journée scientifique du CLARA "Cancéropôle Lyon Auvergne Rhône-Alpes", Mar 2010, Lyon, France
Poster de conférence hal-02518843 v1

Identification of a direct interaction between CRMP5 and tubulin involved in neurite outgrowth inhibition

Sébastien Brot , Véronique Rogemond , Valérie Perrot , Naura Chounlamountri , Carole Auger et al.
9ème Colloque de la société des Neurosciences, May 2009, Bordeaux, France
Poster de conférence hal-02518885 v1

Study of CRMP5 properties and its role in the development of cerebral tumors

Sébastien Brot , Celine Malleval , Jérome Honnorat , Mahnaz Moradi-Améli
3ème journée scientifique du CLARA "Cancéropôle Lyon Auvergne Rhône-Alpes", Mar 2008, Lyon, France
Poster de conférence hal-02518895 v1