VL

Vincent LE MOIGNE

40
Documents

Compétences

Monoclonal antibodies

Publications

Publications

A glycosylated lipooctapeptide promotes uptake and growth of Mycobacterium abscessus in the host

Louis David Leclercq , Vincent Le Moigne , Wassim Daher , Mélanie Cortes , Bertus Viljoen et al.
Nature Communications, 2025, 16, pp.3326. ⟨10.1038/s41467-025-58455-5⟩
Article dans une revue hal-05034871 v1
Image document

Deletion of ESX-3 and ESX-4 secretion systems in Mycobacterium abscessus results in highly impaired pathogenicity

Wassim Daher , Vincent Le Moigne , Yara Tasrini , Shweta Parmar , Danielle Sexton et al.
Communications Biology, 2025, 8 (1), pp.166. ⟨10.1038/s42003-025-07572-4⟩
Article dans une revue hal-04961581 v1

In vitro, intracellular and in vivo s ynergy between amoxicillin, imipenem and relebactam against Mycobacterium abscessus

Maria Bitar , Vincent Le Moigne , Jean-Louis Herrmann , Michel Arthur , Jean-Luc Mainardi
Journal of Antimicrobial Chemotherapy, 2025, ⟨10.1093/jac/dkaf101⟩
Article dans une revue hal-05019510 v1
Image document

Cyclophostin and Cyclipostins analogues counteract macrolide-induced resistance mediated by erm(41) in Mycobacterium abscessus

Morgane Sarrazin , Isabelle Poncin , Patrick Fourquet , Stéphane Audebert , Luc Camoin et al.
Journal of Biomedical Science, 2024, 31 (1), pp.103. ⟨10.1186/s12929-024-01091-w⟩
Article dans une revue inserm-04841571 v1
Image document

Exploration of the role of the penicillin binding protein 2c (Pbp2c) in inducible β-lactam resistance in Corynebacteriaceae

Marie Lavollay , Céline Buon , Vincent Le Moigne , Fabrice Compain , Armel Guyonvarch et al.
Frontiers in Microbiology, 2024, 15, pp.1327723. ⟨10.3389/fmicb.2024.1327723⟩
Article dans une revue hal-04574922 v1
Image document

The ESX-4 substrates, EsxU and EsxT, modulate Mycobacterium abscessus fitness

Marion Lagune , Vincent Le Moigne , Matt Johansen , Flor Vásquez Sotomayor , Wassim Daher et al.
PLoS Pathogens, 2022, 18 (8), pp.e1010771. ⟨10.1371/journal.ppat.1010771⟩
Article dans une revue hal-03751522 v1
Image document

IgA Serological Response for the Diagnosis of Mycobacterium abscessus Infections in Patients with Cystic Fibrosis

Vincent Le Moigne , Anne-Laure Roux , Hélène Mahoudo , Gaëtan Christien , Agnès Ferroni et al.
Microbiology Spectrum, 2022, 10 (3), pp.00192-22. ⟨10.1128/spectrum.00192-22⟩
Article dans une revue hal-03682405 v1

Roscovitine Worsens Mycobacterium abscessus Infection by Reducing DUOX2-mediated Neutrophil Response

Vincent Le Moigne , Daniela Rodriguez Rincon , Simon Glatigny , Christian M. Dupont , Christelle Langevin et al.
American Journal of Respiratory Cell and Molecular Biology, 2022, 66 (4), pp.439-451. ⟨10.1165/rcmb.2021-0406OC⟩
Article dans une revue hal-03673642 v1
Image document

Liposomal Amikacin and Mycobacterium abscessus: Intimate interactions inside eukaryotic cells

Vincent Le Moigne , Sabine Blouquit-Laye , Aurore Desquesnes , Fabienne Girard-Misguich , Jean-Louis Herrmann
Journal of Antimicrobial Chemotherapy, 2022, ⟨10.1093/jac/dkac348⟩
Article dans une revue hal-03789988 v1
Image document

Serological biomarkers for the diagnosis of Mycobacterium abscessus infections in cystic fibrosis patients

Vincent Le Moigne , Anne-Laure Roux , Hélène Mahoudo , Gaëtan Christien , Agnès Ferroni et al.
Journal of Cystic Fibrosis, 2021, 21 (2), ⟨10.1016/j.jcf.2021.08.019⟩
Article dans une revue hal-03348005 v1
Image document

Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors

Jérôme Ruyck , Christian Dupont , Elodie Lamy , Vincent Le Moigne , Christophe Biot et al.
ChemistryOpen, 2020, 9 (3), pp.351-365. ⟨10.1002/open.202000042⟩
Article dans une revue hal-02988322 v1
Image document

Efficacy of bedaquiline, alone or in combination with imipenem, against Mycobacterium abscessusin C3HeB/FeJ mice

Vincent Le Moigne , Clément Raynaud , Flavie Moreau , Christian Dupont , Jérôme Nigou et al.
Antimicrobial Agents and Chemotherapy, 2020, 64 (6), ⟨10.1128/AAC.00114-20⟩
Article dans une revue hal-03032987 v1
Image document

A TLR2-Activating Fraction From Mycobacterium abscessus Rough Variant Demonstrates Vaccine and Diagnostic Potential

Vincent Le Moigne , Anne-Laure Roux , Aude Jobart-Malfait , Landry Blanc , Karima Chaoui et al.
Frontiers in Cellular and Infection Microbiology, 2020, 10, ⟨10.3389/fcimb.2020.00432⟩
Article dans une revue hal-03031741 v1
Image document

Cyclipostins and Cyclophostin Analogues as Multitarget Inhibitors That Impair Growth of Mycobacterium abscessus

Abdeldjalil Madani , Jeremy Ridenour , Benjamin Martin , Rishi Paudel , Anosha Abdul Basir et al.
ACS Infectious Diseases, 2019, ⟨10.1021/acsinfecdis.9b00172⟩
Article dans une revue hal-02276160 v1
Image document

Lsr2 Is an Important Determinant of Intracellular Growth and Virulence in Mycobacterium abscessus

Vincent Le Moigne , Audrey Bernut , Mélanie Cortes , Albertus Viljoen , Christian Dupont et al.
Frontiers in Microbiology, 2019, 10, pp.905. ⟨10.3389/fmicb.2019.00905⟩
Article dans une revue pasteur-02618218 v1
Image document

Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

Violaine Dubois , Alexandre Pawlik , Anouchka Bories , Vincent Le Moigne , Odile Sismeiro et al.
PLoS Pathogens, 2019, 15 (11), pp.e1008069. ⟨10.1371/journal.ppat.1008069⟩
Article dans une revue hal-02379161 v1

MmpL8 MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family

Violaine Dubois , Albertus Viljoen , Laura Laencina , Vincent Le Moigne , Audrey Bernut et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (43), pp.E10147-E10156. ⟨10.1073/pnas.1812984115⟩
Article dans une revue hal-02137509 v1

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Violaine Dubois , Laura Laencina , Anouchka Bories , Vincent Le Moigne , Alexandre Pawlik et al.
Journal of visualized experiments : JoVE, 2018, 139, pp.57766. ⟨10.3791/57766⟩
Article dans une revue pasteur-02618229 v1

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus

Laura Laencina , Violaine Dubois , Vincent Le Moigne , Albertus Viljoen , Laleh Majlessi et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (5), pp.E1002-E1011. ⟨10.1073/pnas.1713195115⟩
Article dans une revue pasteur-02046027 v1
Image document

ESX-4, un système de sécrétion mycobactérien ancestral, essentiel pour la croissance de Mycobacterium abscessus dans les phagocytes environnementaux et humains

Fabienne Girard-Misguich , Laura Laencina , Violaine Dubois , Vincent Le Moigne , Laurent Kremer et al.
Médecine/Sciences, 2018, 34 (10), pp.795-797. ⟨10.1051/medsci/2018196⟩
Article dans une revue pasteur-02046117 v1
Image document

Inhibition of the β-Lactamase Bla <sub>Mab</sub> by Avibactam Improves the <i>In Vitro</i> and <i>In Vivo</i> Efficacy of Imipenem against Mycobacterium abscessus

Anne-Laure Lefebvre , Vincent Le Moigne , Audrey Bernut , Carole Veckerlé , Fabrice Compain et al.
Antimicrobial Agents and Chemotherapy, 2017, 61 (4), pp.e02440-16. ⟨10.1128/aac.02440-16⟩
Article dans une revue hal-03680922 v1
Image document

Vaccine strategies against cystic fibrosis pathogens

Vincent Le Moigne , Jean-Louis Gaillard , Jean-Louis Herrmann
Human Vaccines & Immunotherapeutics, 2016, 12 (3), pp.751 - 756. ⟨10.1080/21645515.2015.1102810⟩
Article dans une revue hal-03680920 v1

MgtC as a Host-Induced Factor and Vaccine Candidate against Mycobacterium abscessus Infection

Vincent Le Moigne , Claudine Belon , Céline Goulard , Geoffrey Accard , Audrey Bernut et al.
Infection and Immunity, 2016, 84 (10), pp.2895-2903. ⟨10.1128/IAI.00359-16⟩
Article dans une revue hal-02283984 v1

Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent

Iman Halloum , Severine Carrere-Kremer , Mickaël Blaise , Albertus Viljoen , Audrey Bernut et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (29), pp.E4228-E4237. ⟨10.1073/pnas.1605477113⟩
Article dans une revue hal-02086925 v1

Vaccine strategies against bacterial pathogens in cystic fibrosis patients

Vincent Le Moigne , Jean-Louis Gaillard , Jean-Louis Herrmann
Médecine et Maladies Infectieuses, 2016, 46 (1), pp.4-9. ⟨10.1016/j.medmal.2015.11.013⟩
Article dans une revue hal-03685287 v1
Image document

Vaccine strategies against bacterial pathogens in cystic fibrosis patients

V. Le Moigne , J.-L. Gaillard , J.-L. Herrmann
Médecine et Maladies Infectieuses, 2015, 46 (1), pp.4 - 9. ⟨10.1016/j.medmal.2015.11.013⟩
Article dans une revue hal-03680918 v1
Image document

Targeted Collection of Plasmid DNA in Large and Growing Animal Muscles 6 Weeks after DNA Vaccination with and without Electroporation

Daniel Dory , Vincent Le Moigne , Roland Cariolet , Véronique Béven , André Keranflec et al.
Journal of Immunology Research, 2015
Article dans une revue hal-03715864 v1
Image document

Mycobacterium abscessus Phospholipase C Expression Is Induced during Coculture within Amoebae and Enhances M. abscessus Virulence in Mice

Jean Bakala N'Goma , Vincent Le Moigne , Nathalie Soismier , Laura Laencina , Fabien Le Chevalier et al.
Infection and Immunity, 2015, 83, pp.780 - 791. ⟨10.1128/iai.02032-14⟩
Article dans une revue hal-03680916 v1

Bacterial phospholipases C as vaccine candidate antigens against cystic fibrosis respiratory pathogens: the Mycobacterium abscessus model

Vincent Le Moigne , Martin Rottman , Céline Goulard , Benoît Barteau , Isabelle Poncin et al.
Vaccine, 2015, Equipe 7, 33 (18), pp.2118--2124. ⟨10.1016/j.vaccine.2015.03.030⟩
Article dans une revue hal-01830970 v1

Mycobacterium abscessus Phospholipase C Expression Is Induced during Coculture within Amoebae and Enhances M. abscessus Virulence in Mice

Jean Claude Bakala N'Goma , Vincent Le Moigne , Nathalie Soismier , Laura Laencina , Fabien Le Chevalier et al.
Infection and Immunity, 2015, 83 (2), pp.780-791. ⟨10.1128/IAI.02032-14⟩
Article dans une revue hal-03550943 v1

In Vivo Assessment of Drug Efficacy against Mycobacterium abscessus Using the Embryonic Zebrafish Test System

Audrey Bernut , Vincent Le Moigne , Tiffany Lesne , Georges Lutfalla , Jean-Louis Herrmann et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (7), pp.4054-4063. ⟨10.1128/AAC.00142-14⟩
Article dans une revue hal-03688520 v1
Image document

In Vivo Assessment of Drug Efficacy against Mycobacterium abscessus Using the Embryonic Zebrafish Test System

Audrey Bernut , Vincent Le Moigne , Tiffany Lesne , Georges Lutfalla , Jean-Louis Herrmann et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (7), pp.4054-4063. ⟨10.1128/AAC.00142-14⟩
Article dans une revue hal-02088311 v1
Image document

<i>In Vivo</i> Assessment of Drug Efficacy against Mycobacterium abscessus Using the Embryonic Zebrafish Test System

Audrey Bernut , Vincent Le Moigne , Tiffany Lesne , Georges Lutfalla , Jean-Louis Herrmann et al.
Antimicrobial Agents and Chemotherapy, 2014, 58, pp.4054 - 4063. ⟨10.1128/aac.00142-14⟩
Article dans une revue hal-03680924 v1

Detection and quantification of staphylococcal enterotoxin A in foods with specific and sensitive polyclonal antibodies

Marie-Clarisse Techer , Michèle Salmain , Olivier Tranquet , Valerie Echasserieau , Vincent Le Moigne et al.
Food Control, 2013, 32 (1), pp.255 - 261. ⟨10.1016/j.foodcont.2012.11.021⟩
Article dans une revue istex hal-01208625 v1
Image document

Absence of amplification role of the protein KLH on antibody response generated by a MAP Staphyloccocus aureus enterotoxin A (SEA) peptide comparing with the corresponding monomeric peptide

Vincent Le Moigne
Journal of Immunological Methods, 2011, 365 (1-2), pp.110-117. ⟨10.1016/j.jim.2010.12.003⟩
Article dans une revue hal-03712240 v1

Piezoelectricimmunosensor for direct and rapiddetection of staphylococcal enterotoxin A (SEA) at the ng level

Michèle Salmain , Mahsa Ghasemi , Souhir Boujday , Jolanda Spadavecchia , Marie-Clarisse Techer et al.
Biosensors and Bioelectronics, 2011, 29 (1), pp.140-144. ⟨10.1016/j.bios.2011.08.007⟩
Article dans une revue istex hal-00680966 v1
Image document

Biosafety of DNA vaccines: New generation of DNA vectors and current knowledge on the fate of plasmids after injection.

Florence Faurez , Daniel Dory , Vincent Le Moigne , Rodolphe Gravier , André Jestin
Vaccine, 2010, 28 (23), pp.3888-95. ⟨10.1016/j.vaccine.2010.03.040⟩
Article dans une revue hal-00493412 v1
Image document

Immune Response to Chlamydophila abortus POMP91B Protein in the Context of Different Pathogen Associated Molecular Patterns (PAMP); Role of Antigen in the Orientation of Immune Response

Vincent Le Moigne , Georges Robreau , Wahib Mahana
Toxins, 2009, 1 (2), pp.59 - 73. ⟨10.3390/toxins1020059⟩
Article dans une revue hal-03712031 v1
Image document

P27-PPE36 (Rv2108) Mycobacterium tuberculosis Antigen – Member of PPE Protein Family with Surface Localization and Immunological Activities

Vincent Le Moigne , Wahib Mahana
Understanding Tuberculosis - Analyzing the Origin of Mycobacterium Tuberculosis Pathogenicity, InTech, pp.539-560, 2012, Understanding Tuberculosis – Analyzing the Origin of Mycobacterium Tuberculosis Pathogenicity, ⟨10.5772/31806⟩
Chapitre d'ouvrage hal-03713603 v1