VL

Vincent LE MOIGNE

Vincent LE MOIGNE
38
Documents
Identifiants chercheurs

Compétences

Monoclonal antibodies Animal model

Publications

Publications

In vitro, intracellular and in vivo s ynergy between amoxicillin, imipenem and relebactam against Mycobacterium abscessus

Maria Bitar , Vincent Le Moigne , Jean-Louis Herrmann , Michel Arthur , Jean-Luc Mainardi

Journal of Antimicrobial Chemotherapy, 2025, ⟨10.1093/jac/dkaf101⟩

Article dans une revue hal-05019510v1
Deposit thumbnail

Deletion of ESX-3 and ESX-4 secretion systems in Mycobacterium abscessus results in highly impaired pathogenicity

Wassim Daher , Vincent Le Moigne , Yara Tasrini , Shweta Parmar , Danielle Sexton et al.

Communications Biology, 2025, 8 (1), pp.166. ⟨10.1038/s42003-025-07572-4⟩

Article dans une revue hal-04961581v1
Deposit thumbnail

A glycosylated lipooctapeptide promotes uptake and growth of Mycobacterium abscessus in the host

Louis David Leclercq , Vincent Le Moigne , Wassim Daher , Mélanie Cortes , Bertus Viljoen et al.

Nature Communications, 2025, 16 (1), pp.3326. ⟨10.1038/s41467-025-58455-5⟩

Article dans une revue hal-05034871v1
Deposit thumbnail

The addition of amoxicillin improves the efficacy of the imipenem-avibactam combination against Mycobacterium abscessus in a mouse model of infection

Vincent Le Moigne , Maria Bitar , Michel Arthur , Jean-Luc Mainardi , Jean-Louis Herrmann

Antimicrobial Agents and Chemotherapy, 2025, 69 (8), pp.e0053425. ⟨10.1128/aac.00534-25⟩

Article dans une revue hal-05173967v1
Deposit thumbnail

Exploration of the role of the penicillin binding protein 2c (Pbp2c) in inducible β-lactam resistance in Corynebacteriaceae

Marie Lavollay , Céline Buon , Vincent Le Moigne , Fabrice Compain , Armel Guyonvarch et al.

Frontiers in Microbiology, 2024, 15, pp.1327723. ⟨10.3389/fmicb.2024.1327723⟩

Article dans une revue hal-04574922v1
Deposit thumbnail

Cyclophostin and Cyclipostins analogues counteract macrolide-induced resistance mediated by erm(41) in Mycobacterium abscessus

Morgane Sarrazin , Isabelle Poncin , Patrick Fourquet , Stéphane Audebert , Luc Camoin et al.

Journal of Biomedical Science, 2024, 31 (1), pp.103. ⟨10.1186/s12929-024-01091-w⟩

Article dans une revue inserm-04841571v1
Deposit thumbnail

IgA Serological Response for the Diagnosis of Mycobacterium abscessus Infections in Patients with Cystic Fibrosis

Vincent Le Moigne , Anne-Laure Roux , Hélène Mahoudo , Gaëtan Christien , Agnès Ferroni et al.

Microbiology Spectrum, 2022, 10 (3), pp.00192-22. ⟨10.1128/spectrum.00192-22⟩

Article dans une revue hal-03682405v1

Roscovitine Worsens Mycobacterium abscessus Infection by Reducing DUOX2-mediated Neutrophil Response

Vincent Le Moigne , Daniela Rodriguez Rincon , Simon Glatigny , Christian M. Dupont , Christelle Langevin et al.

American Journal of Respiratory Cell and Molecular Biology, 2022, 66 (4), pp.439-451. ⟨10.1165/rcmb.2021-0406OC⟩

Article dans une revue hal-03673642v1
Deposit thumbnail

Liposomal Amikacin and Mycobacterium abscessus: Intimate interactions inside eukaryotic cells

Vincent Le Moigne , Sabine Blouquit-Laye , Aurore Desquesnes , Fabienne Girard-Misguich , Jean-Louis Herrmann

Journal of Antimicrobial Chemotherapy, 2022, ⟨10.1093/jac/dkac348⟩

Article dans une revue hal-03789988v1
Deposit thumbnail

The ESX-4 substrates, EsxU and EsxT, modulate Mycobacterium abscessus fitness

Marion Lagune , Vincent Le Moigne , Matt Johansen , Flor Vásquez Sotomayor , Wassim Daher et al.

PLoS Pathogens, 2022, 18 (8), pp.e1010771. ⟨10.1371/journal.ppat.1010771⟩

Article dans une revue hal-03751522v1
Deposit thumbnail

Serological biomarkers for the diagnosis of Mycobacterium abscessus infections in cystic fibrosis patients

Vincent Le Moigne , Anne-Laure Roux , Hélène Mahoudo , Gaëtan Christien , Agnès Ferroni et al.

Journal of Cystic Fibrosis, 2021, 21 (2), ⟨10.1016/j.jcf.2021.08.019⟩

Article dans une revue hal-03348005v1
Deposit thumbnail

Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors

Jérôme Ruyck , Christian Dupont , Elodie Lamy , Vincent Le Moigne , Christophe Biot et al.

ChemistryOpen, 2020, 9 (3), pp.351-365. ⟨10.1002/open.202000042⟩

Article dans une revue hal-02988322v1
Deposit thumbnail

Efficacy of bedaquiline, alone or in combination with imipenem, against Mycobacterium abscessusin C3HeB/FeJ mice

Vincent Le Moigne , Clément Raynaud , Flavie Moreau , Christian Dupont , Jérôme Nigou et al.

Antimicrobial Agents and Chemotherapy, 2020, 64 (6), ⟨10.1128/AAC.00114-20⟩

Article dans une revue hal-03032987v1
Deposit thumbnail

A TLR2-Activating Fraction From Mycobacterium abscessus Rough Variant Demonstrates Vaccine and Diagnostic Potential

Vincent Le Moigne , Anne-Laure Roux , Aude Jobart-Malfait , Landry Blanc , Karima Chaoui et al.

Frontiers in Cellular and Infection Microbiology, 2020, 10, ⟨10.3389/fcimb.2020.00432⟩

Article dans une revue hal-03031741v1
Deposit thumbnail

Cyclipostins and Cyclophostin Analogues as Multitarget Inhibitors That Impair Growth of Mycobacterium abscessus

Abdeldjalil Madani , Jeremy Ridenour , Benjamin Martin , Rishi Paudel , Anosha Abdul Basir et al.

ACS Infectious Diseases, 2019, ⟨10.1021/acsinfecdis.9b00172⟩

Article dans une revue hal-02276160v1
Deposit thumbnail

Lsr2 Is an Important Determinant of Intracellular Growth and Virulence in Mycobacterium abscessus

Vincent Le Moigne , Audrey Bernut , Mélanie Cortes , Albertus Viljoen , Christian Dupont et al.

Frontiers in Microbiology, 2019, 10, pp.905. ⟨10.3389/fmicb.2019.00905⟩

Article dans une revue pasteur-02618218v1
Deposit thumbnail

Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

Violaine Dubois , Alexandre Pawlik , Anouchka Bories , Vincent Le Moigne , Odile Sismeiro et al.

PLoS Pathogens, 2019, 15 (11), pp.e1008069. ⟨10.1371/journal.ppat.1008069⟩

Article dans une revue hal-02379161v1

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Violaine Dubois , Laura Laencina , Anouchka Bories , Vincent Le Moigne , Alexandre Pawlik et al.

Journal of visualized experiments : JoVE, 2018, 139, pp.57766. ⟨10.3791/57766⟩

Article dans une revue pasteur-02618229v1

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus

Laura Laencina , Violaine Dubois , Vincent Le Moigne , Albertus Viljoen , Laleh Majlessi et al.

Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (5), pp.E1002-E1011. ⟨10.1073/pnas.1713195115⟩

Article dans une revue pasteur-02046027v1
Deposit thumbnail

ESX-4, un système de sécrétion mycobactérien ancestral, essentiel pour la croissance de Mycobacterium abscessus dans les phagocytes environnementaux et humains

Fabienne Girard-Misguich , Laura Laencina , Violaine Dubois , Vincent Le Moigne , Laurent Kremer et al.

Médecine/Sciences, 2018, 34 (10), pp.795-797. ⟨10.1051/medsci/2018196⟩

Article dans une revue pasteur-02046117v1

MmpL8 MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family

Violaine Dubois , Albertus Viljoen , Laura Laencina , Vincent Le Moigne , Audrey Bernut et al.

Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (43), pp.E10147-E10156. ⟨10.1073/pnas.1812984115⟩

Article dans une revue hal-02137509v1
Deposit thumbnail

Inhibition of the β-Lactamase Bla <sub>Mab</sub> by Avibactam Improves the <i>In Vitro</i> and <i>In Vivo</i> Efficacy of Imipenem against Mycobacterium abscessus

Anne-Laure Lefebvre , Vincent Le Moigne , Audrey Bernut , Carole Veckerlé , Fabrice Compain et al.

Antimicrobial Agents and Chemotherapy, 2017, 61 (4), pp.e02440-16. ⟨10.1128/aac.02440-16⟩

Article dans une revue hal-03680922v1

Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent

Iman Halloum , Severine Carrere-Kremer , Mickaël Blaise , Albertus Viljoen , Audrey Bernut et al.

Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (29), pp.E4228-E4237. ⟨10.1073/pnas.1605477113⟩

Article dans une revue hal-02086925v1

MgtC as a Host-Induced Factor and Vaccine Candidate against Mycobacterium abscessus Infection

Vincent Le Moigne , Claudine Belon , Céline Goulard , Geoffrey Accard , Audrey Bernut et al.

Infection and Immunity, 2016, 84 (10), pp.2895-2903. ⟨10.1128/IAI.00359-16⟩

Article dans une revue hal-02283984v1
Deposit thumbnail

Vaccine strategies against cystic fibrosis pathogens

Vincent Le Moigne , Jean-Louis Gaillard , Jean-Louis Herrmann

Human Vaccines & Immunotherapeutics, 2016, 12 (3), pp.751 - 756. ⟨10.1080/21645515.2015.1102810⟩

Article dans une revue hal-03680920v1
Deposit thumbnail

Mycobacterium abscessus Phospholipase C Expression Is Induced during Coculture within Amoebae and Enhances M. abscessus Virulence in Mice

Jean Bakala N'Goma , Vincent Le Moigne , Nathalie Soismier , Laura Laencina , Fabien Le Chevalier et al.

Infection and Immunity, 2015, 83, pp.780 - 791. ⟨10.1128/iai.02032-14⟩

Article dans une revue hal-03680916v1

Bacterial phospholipases C as vaccine candidate antigens against cystic fibrosis respiratory pathogens: the Mycobacterium abscessus model

Vincent Le Moigne , Martin Rottman , Céline Goulard , Benoît Barteau , Isabelle Poncin et al.

Vaccine, 2015, Equipe 7, 33 (18), pp.2118--2124. ⟨10.1016/j.vaccine.2015.03.030⟩

Article dans une revue istex hal-01830970v1
Deposit thumbnail

Targeted Collection of Plasmid DNA in Large and Growing Animal Muscles 6 Weeks after DNA Vaccination with and without Electroporation

Daniel Dory , Vincent Le Moigne , Roland Cariolet , Véronique Béven , André Keranflec et al.

Journal of Immunology Research, 2015

Article dans une revue hal-03715864v1
Deposit thumbnail

Vaccine strategies against bacterial pathogens in cystic fibrosis patients

V. Le Moigne , J.-L. Gaillard , J.-L. Herrmann

Médecine et Maladies Infectieuses (1971-2020), 2015, 46 (1), pp.4 - 9. ⟨10.1016/j.medmal.2015.11.013⟩

Article dans une revue hal-03680918v1
Deposit thumbnail

In Vivo Assessment of Drug Efficacy against Mycobacterium abscessus Using the Embryonic Zebrafish Test System

Audrey Bernut , Vincent Le Moigne , Tiffany Lesne , Georges Lutfalla , Jean-Louis Herrmann et al.

Antimicrobial Agents and Chemotherapy, 2014, 58 (7), pp.4054-4063. ⟨10.1128/AAC.00142-14⟩

Article dans une revue hal-02088311v1
Deposit thumbnail

<i>In Vivo</i> Assessment of Drug Efficacy against Mycobacterium abscessus Using the Embryonic Zebrafish Test System

Audrey Bernut , Vincent Le Moigne , Tiffany Lesne , Georges Lutfalla , Jean-Louis Herrmann et al.

Antimicrobial Agents and Chemotherapy, 2014, 58, pp.4054 - 4063. ⟨10.1128/aac.00142-14⟩

Article dans une revue hal-03680924v1

Detection and quantification of staphylococcal enterotoxin A in foods with specific and sensitive polyclonal antibodies

Marie-Clarisse Techer , Michèle Salmain , Olivier Tranquet , Valerie Echasserieau , Vincent Le Moigne et al.

Food Control, 2013, 32 (1), pp.255 - 261. ⟨10.1016/j.foodcont.2012.11.021⟩

Article dans une revue istex hal-01208625v1

Piezoelectricimmunosensor for direct and rapiddetection of staphylococcal enterotoxin A (SEA) at the ng level

Michèle Salmain , Mahsa Ghasemi , Souhir Boujday , Jolanda Spadavecchia , Marie-Clarisse Techer et al.

Biosensors and Bioelectronics, 2011, 29 (1), pp.140-144. ⟨10.1016/j.bios.2011.08.007⟩

Article dans une revue istex hal-00680966v1
Deposit thumbnail

Absence of amplification role of the protein KLH on antibody response generated by a MAP Staphyloccocus aureus enterotoxin A (SEA) peptide comparing with the corresponding monomeric peptide

Vincent Le Moigne

Journal of Immunological Methods, 2011, 365 (1-2), pp.110-117. ⟨10.1016/j.jim.2010.12.003⟩

Article dans une revue hal-03712240v1
Deposit thumbnail

Biosafety of DNA vaccines: New generation of DNA vectors and current knowledge on the fate of plasmids after injection.

Florence Faurez , Daniel Dory , Vincent Le Moigne , Rodolphe Gravier , André Jestin

Vaccine, 2010, 28 (23), pp.3888-95. ⟨10.1016/j.vaccine.2010.03.040⟩

Article dans une revue hal-00493412v1
Deposit thumbnail

Immune Response to Chlamydophila abortus POMP91B Protein in the Context of Different Pathogen Associated Molecular Patterns (PAMP); Role of Antigen in the Orientation of Immune Response

Vincent Le Moigne , Georges Robreau , Wahib Mahana

Toxins, 2009, 1 (2), pp.59 - 73. ⟨10.3390/toxins1020059⟩

Article dans une revue hal-03712031v1
Deposit thumbnail

P27-PPE36 (Rv2108) Mycobacterium tuberculosis Antigen – Member of PPE Protein Family with Surface Localization and Immunological Activities

Vincent Le Moigne , Wahib Mahana

Understanding Tuberculosis - Analyzing the Origin of Mycobacterium Tuberculosis Pathogenicity, InTech, pp.539-560, 2012, Understanding Tuberculosis – Analyzing the Origin of Mycobacterium Tuberculosis Pathogenicity, ⟨10.5772/31806⟩

Chapitre d'ouvrage hal-03713603v1