VS

Violaine Sée

75%
Libre accès
40
Documents
Affiliations actuelles
  • University of Liverpool
  • Université Louis Pasteur - Strasbourg I
  • Université Claude Bernard Lyon 1 (UCBL)
Identifiants chercheurs
Contact

Présentation

My research focuses on the cellular response to environmental oxygen level variations and their impact on cell fate. I have worked for 19 years at the University of Liverpool, where I investigated the role of hypoxia on cancer cell phenotype, especially in paediatric (neuroblastoma, medulloblastoma) and adult brain tumours (glioblastoma). In 2021, I have joined the University Claude Bernard Lyon 1, where I work on the role of hypoxa on skin cells, in the context of skin ageing, wound healing and dermal fibrosis.


Compétences

Cell signalling, fluorescence microscopy, hypoxia

Publications

Publications

Optical Tissue Clearing to Study the Intra-Pulmonary Biodistribution of Intravenously Delivered Mesenchymal Stromal Cells and Their Interactions with Host Lung Cells

Alejandra Hernandez Pichardo , Francesco Amadeo , Bettina Wilm , Raphaël Lévy , Lorenzo Ressel et al.
International Journal of Molecular Sciences, 2022, 23 (22), pp.14171. ⟨10.3390/ijms232214171⟩
Article dans une revue hal-04852359 v1

Downregulation of both mismatch repair and non-homologous end-joining pathways in hypoxic brain tumour cell lines

Sophie Cowman , Barry Pizer , Violaine Sée
PeerJ, 2021, 9, pp.e11275. ⟨10.7717/peerj.11275⟩
Article dans une revue hal-04852363 v1
Image document

Oxygen-dependent changes in binding partners and post-translational modifications regulate the abundance and activity of HIF-1α/2α

Leonard Daly , Philip Brownridge , Michael Batie , Sonia Rocha , Violaine Sée et al.
Science Signaling, 2021, 14 (692), ⟨10.1126/scisignal.abf6685⟩
Article dans une revue hal-04843131 v1
Image document

The Role of Hypoxia-Inducible Factor Post-Translational Modifications in Regulating Its Localisation, Stability, and Activity

Adam Albanese , Leonard A Daly , Daniela Mennerich , Thomas Kietzmann , Violaine Sée
International Journal of Molecular Sciences, 2020, 22, ⟨10.3390/ijms22010268⟩
Article dans une revue hal-04843156 v1

Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells

Sophie Cowman , Yuen Ngan Fan , Barry Pizer , Violaine Sée
BMC Cancer, 2019, 19 (1), pp.300. ⟨10.1186/s12885-019-5476-9⟩
Article dans une revue hal-04843297 v1

CDK inhibitors reduce cell proliferation and reverse hypoxia-induced metastasis of neuroblastoma tumours in a chick embryo model

Rasha Swadi , Keerthika Sampat , Anne Herrmann , Paul Losty , Violaine Sée et al.
Scientific Reports, 2019, 9 (1), pp.9136. ⟨10.1038/s41598-019-45571-8⟩
Article dans une revue hal-04843291 v1

Optimising the chick chorioallantoic membrane xenograft model of neuroblastoma for drug delivery

Rasha Swadi , Grace Mather , Barry Pizer , Paul Losty , Violaine Sée et al.
BMC Cancer, 2018, 18 (1), pp.28. ⟨10.1186/s12885-017-3978-x⟩
Article dans une revue hal-04843310 v1

Magnetic Resonance Imaging for Characterization of a Chick Embryo Model of Cancer Cell Metastases

Anne Herrmann , Arthur Taylor , Patricia Murray , Harish Poptani , Violaine Sée
Molecular Imaging, 2018, 17, ⟨10.1177/1536012118809585⟩
Article dans une revue hal-04843301 v1

Effects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model

Yousef Al-Mutawa , Anne Herrmann , Catriona Corbishley , Paul D. Losty , Marie Phelan et al.
Bioscience Reports, 2018, 38 (4), ⟨10.1042/BSR20180185⟩
Article dans une revue hal-04843306 v1

Use of infrared microspectroscopy to elucidate a specific chemical signature associated with hypoxia levels found in glioblastoma

Christophe Sandt , Céline Nadaradjane , Rosalie Richards , Paul Dumas , Violaine Sée
Analyst, 2016, 141 (3), pp.870-883. ⟨10.1039/c5an02112j⟩
Article dans une revue hal-04843341 v1

Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and -2 alpha impacts on their stability and mobility

S. Taylor , J. Bagnall , D. Mason , R. Levy , D. Fernig et al.
Open Biology, 2016, 6 (9), pp.160195. ⟨10.1098/rsob.160195⟩
Article dans une revue hal-04843316 v1

Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation

John Ankers , Raheela Awais , Nicholas Jones , James Boyd , Sheila Ryan et al.
Article dans une revue hal-04843333 v1

Cell cycle progression in glioblastoma cells is unaffected by pathophysiological levels of hypoxia

Rosalie Richards , Michael Jenkinson , Brian Haylock , Violaine Sée
PeerJ, 2016, 4, pp.e1755. ⟨10.7717/peerj.1755⟩
Article dans une revue hal-04843336 v1

Cellular memory of hypoxia elicits neuroblastoma metastasis and enables invasion by non-aggressive neighbouring cells

A Herrmann , M Rice , R Lévy , B Pizer , P Losty et al.
Oncogenesis, 2015, 4 (2), pp.e138-e138. ⟨10.1038/oncsis.2014.52⟩
Article dans une revue hal-04843361 v1

Modeling the dynamics of hypoxia inducible factor-1α (HIF-1α) within single cells and 3D cell culture systems

Joseph Leedale , Anne Herrmann , James Bagnall , Andreas Fercher , Dmitri Papkovsky et al.
Mathematical Biosciences, 2014, 258, pp.33-43. ⟨10.1016/j.mbs.2014.09.007⟩
Article dans une revue hal-04843357 v1
Image document

Mir-34a Mimics Are Potential Therapeutic Agents for p53-Mutated and Chemo-Resistant Brain Tumour Cells

Yuen Ngan Fan , Daniel Meley , Barry Pizer , Violaine Sée
PLoS ONE, 2014, 9 (9), pp.e108514. ⟨10.1371/journal.pone.0108514⟩
Article dans une revue hal-04843363 v1

Assessing the Efficacy of Nano- and Micro-Sized Magnetic Particles as Contrast Agents for MRI Cell Tracking

Arthur Taylor , Anne Herrmann , Diana Moss , Violaine Sée , Karen Davies et al.
PLoS ONE, 2014, 9 (6), pp.e100259. ⟨10.1371/journal.pone.0100259⟩
Article dans une revue hal-04843346 v1

Tight Control of Hypoxia-inducible Factor-α Transient Dynamics Is Essential for Cell Survival in Hypoxia

James Bagnall , Joseph Leedale , Sarah Taylor , David Spiller , Michael R.H. White et al.
Journal of Biological Chemistry, 2014, 289 (9), pp.5549-5564. ⟨10.1074/jbc.M113.500405⟩
Article dans une revue hal-04843370 v1

Quantum Dots Do Not Affect the Behaviour of Mouse Embryonic Stem Cells and Kidney Stem Cells and Are Suitable for Short-Term Tracking

Aleksandra Rak-Raszewska , Marco Marcello , Simon Kenny , David Edgar , Violaine Sée et al.
PLoS ONE, 2012, 7 (3), pp.e32650. ⟨10.1371/journal.pone.0032650⟩
Article dans une revue hal-04843395 v1

Exploitation of chick embryo environments to reprogram MYCN-amplified neuroblastoma cells to a benign phenotype, lacking detectable MYCN expression

R Carter , D Mullassery , Violaine Sée , S Theocharatos , B Pizer et al.
Oncogenesis, 2012, 1 (8), pp.e24-e24. ⟨10.1038/oncsis.2012.24⟩
Article dans une revue hal-04843372 v1

p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

D Meley , D Spiller , M White , H Mcdowell , B Pizer et al.
Cell Death and Disease, 2010, 1 (5), pp.e41-e41. ⟨10.1038/cddis.2010.16⟩
Article dans une revue hal-04843406 v1

Highly Stable Dextran-Coated Quantum Dots for Biomolecular Detection and Cellular Imaging

Robert Wilson , David Spiller , Alison Beckett , Ian Prior , Violaine Sée
Chemistry of Materials, 2010, 22 (23), pp.6361-6369. ⟨10.1021/cm1023635⟩
Article dans une revue hal-04843379 v1

Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles

Željka Krpetić , Paola Nativo , Violaine Sée , Ian Prior , Mathias Brust et al.
Nano Letters, 2010, 10 (11), pp.4549-4554. ⟨10.1021/nl103142t⟩
Article dans une revue hal-04843382 v1

Self-association of Calcium-binding Protein S100A4 and Metastasis

Thamir Ismail , Shu Zhang , David Fernig , Stephane Gross , Marisa Martin-Fernandez et al.
Journal of Biological Chemistry, 2010, 285 (2), pp.914-922. ⟨10.1074/jbc.M109.010892⟩
Article dans une revue hal-04843388 v1

VEGF Stimulates RCAN1.4 Expression in Endothelial Cells via a Pathway Requiring Ca2+/Calcineurin and Protein Kinase C-δ

Katherine Holmes , Elinor Chapman , Violaine Sée , Michael Cross
PLoS ONE, 2010, 5 (7), pp.e11435. ⟨10.1371/journal.pone.0011435⟩
Article dans une revue hal-04843403 v1

Gold nanoparticles delivery in mammalian live cells: a critical review

Raphaël Lévy , Umbreen Shaheen , Yann Cesbron , Violaine Sée
Nano Reviews, 2010, 1 (1), pp.4889. ⟨10.3402/nano.v1i0.4889⟩
Article dans une revue hal-04850850 v1

Pulsatile Stimulation Determines Timing and Specificity of NF-κB-Dependent Transcription

Louise Ashall , Caroline Horton , David Nelson , Pawel Paszek , Claire Harper et al.
Science, 2009, 324 (5924), pp.242-246. ⟨10.1126/science.1164860⟩
Article dans une revue hal-04850796 v1

C2‐ceramide and reactive oxygen species inhibit pituitary adenylate cyclase activating polypeptide (PACAP)‐induced cyclic‐AMP‐dependent signalling pathway

Violaine Sée , B. Koch , J. Loeffler
Journal of Neurochemistry, 2008, 76 (3), pp.778-788. ⟨10.1046/j.1471-4159.2001.00106.x⟩
Article dans une revue hal-04850841 v1

HP1α guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation

Irina Panteleeva , Stéphanie Boutillier , Violaine Sée , Dave Spiller , Caroline Rouaux et al.
EMBO Journal, 2007, 26 (15), pp.3616-3628. ⟨10.1038/sj.emboj.7601789⟩
Article dans une revue hal-04850797 v1

Antibody-bound β-amyloid precursor protein stimulates the production of tumor necrosis factor-α and monocyte chemoattractant protein-1 by cortical neurons

Corinne Mbebi , Jose-Luis González de Aguilar , Violaine Sée , Luc Dupuis , Nelly Frossard et al.
Neurobiology of Disease, 2005, 19 (1-2), pp.129-141. ⟨10.1016/j.nbd.2004.11.010⟩
Article dans une revue istex hal-04850802 v1

Oscillations in transcription factor dynamics: a new way to control gene expression

D.E. Nelson , Violaine Sée , G. Nelson , M.R.H. White
Biochemical Society Transactions, 2004, 32 (6), pp.1090-1092. ⟨10.1042/BST0321090⟩
Article dans une revue hal-04850812 v1

Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression

D. Nelson , A. Ihekwaba , M. Elliott , J. Johnson , C. Gibney et al.
Science, 2004, 306 (5696), pp.704-708. ⟨10.1126/science.1099962⟩
Article dans une revue hal-04850820 v1

Calcium-dependent regulation of the cell cycle via a novel MAPK–NF-κB pathway in Swiss 3T3 cells

Violaine Sée , Nina K.M. Rajala , David Spiller , Michael R.H. White
Journal of Cell Biology, 2004, 166 (5), pp.661-672. ⟨10.1083/jcb.200402136⟩
Article dans une revue hal-04850828 v1

Amyloid Precursor Protein Family-induced Neuronal Death Is Mediated by Impairment of the Neuroprotective Calcium/Calmodulin Protein Kinase IV-dependent Signaling Pathway

Corinne Mbebi , Violaine Sée , Luc Mercken , Laurent Pradier , Ulrike Müller et al.
Journal of Biological Chemistry, 2002, 277 (23), pp.20979-20990. ⟨10.1074/jbc.M107948200⟩
Article dans une revue hal-04850831 v1

Oxidative Stress Induces Neuronal Death by Recruiting a Protease and Phosphatase-gated Mechanism

Violaine Sée , Jean-Philippe Loeffler
Journal of Biological Chemistry, 2001, 276 (37), pp.35049-35059. ⟨10.1074/jbc.M104988200⟩
Article dans une revue hal-04850836 v1

Calcium/calmodulin‐dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons

Violaine Sée , Anne-Laurence Boutillier , Haruhiko Bito , Jean-Philippe Loeffler
FASEB Journal, 2001, 15 (1), pp.134-144. ⟨10.1096/fj.00-0106com⟩
Article dans une revue hal-04850838 v1

Live Imaging of Cell Invasion Using a Multicellular Spheroid Model and Light-Sheet Microscopy

Marco Marcello , Rosalie Richards , David Mason , Violaine Sée
Multi-Parametric Live Cell Microscopy of 3D Tissue Models, 1035, Springer International Publishing, pp.155-161, 2017, Advances in Experimental Medicine and Biology, ⟨10.1007/978-3-319-67358-5_11⟩
Chapitre d'ouvrage hal-04843325 v1

The Chorioallantoic Membrane of the Chick Embryo to Assess Tumor Formation and Metastasis

Anne Herrmann , Diana Moss , Violaine Sée
Tumor Angiogenesis Assays, 1464, Springer New York, pp.97-105, 2016, Methods in Molecular Biology, ⟨10.1007/978-1-4939-3999-2_9⟩
Chapitre d'ouvrage hal-04843329 v1