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Evaluation of nonnatural L-iminosugar C,C-glycosides, a new class of C-branched iminosugars, as glycosidase inhibitors
Jérôme Désiré
,
Zakaria Debbah
,
David Gueyrard
,
Jérôme Marrot
,
Yves Blériot
et al.
Article dans une revue
hal-04542506
v1
|
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Synthesis, conformational analysis and glycosidase inhibition of bicyclic nojirimycin C-glycosides based on an octahydrofuro[3,2-b]pyridine motif
Jérôme Désiré
,
Quentin Foucart
,
Ana Poveda
,
Gurvan Gourlaouen
,
Yuna Shimadate
et al.
Article dans une revue
hal-04542825
v1
|
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Stereoselective Access to Iminosugar C, C-Glycosides from 6-Azidoketopyranoses
Zakaria Debbah
,
Jérôme C. Marrot
,
Nicolas Auberger
,
Jérôme Désiré
,
Yves Blériot
Article dans une revue
hal-03775104
v1
|
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Stereoselective Synthesis of 1- C -Diethylphosphonomethyl and -difluoromethyl Iminosugars from Sugar Lactams
Thanh Van Tran
,
Jérôme Désiré
,
Nicolas Auberger
,
Yves Blériot
Article dans une revue
hal-03953681
v1
|
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Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and C -alkylation leads to low micromolar HexAB and NagZ inhibitors
J. Bouquet
,
N. Auberger
,
R. Ashmus
,
D. King
,
A. Bordes
et al.
Article dans une revue
hal-04526197
v1
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Sugar-Derived Amidines and Congeners: Structures, Glycosidase Inhibition and Applications
Yves Blériot
,
Nicolas Auberger
,
Jérôme Désiré
Article dans une revue
(article de synthèse)
hal-04543430
v1
|
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Synthesis and chelation study of a fluoroionophore and a glycopeptide based on an aza crown iminosugar structure
Alexandra Bordes
,
Ana Poveda
,
Nathalie Fontelle
,
Ana Ardá
,
Jérôme Guillard
et al.
Article dans une revue
hal-04336072
v1
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Glycosyl Oxocarbenium Ions: Structure, Conformation, Reactivity, and Interactions
Antonio Franconetti
,
Ana Ardá
,
Juan Luis Asensio
,
Yves Blériot
,
Sébastien Thibaudeau
et al.
Article dans une revue
hal-04542812
v1
|
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Contributing to the Study of Enzymatic and Chemical Glycosyl Transfer Through the Observation and Mimicry of Glycosyl Cations
Yves Blériot
Article dans une revue
hal-04542796
v1
|
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Insight into the Ferrier rearrangement by combining flash chemistry and superacids
Naresh Bhuma
,
Ludivine Lebedel
,
Hiroki Yamashita
,
Yutaka Shimizu
,
Zahra Abada
et al.
Article dans une revue
hal-03007376
v1
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Iminosugar-C-glycosides work as pharmacological chaperones of NAGLU, a glycosidase involved in MPS IIIB rare disease
Sha Zhu
,
Yerri Jagadeesh
,
Anh Tuan Tran
,
Alisdair Boraston
,
Dominic S Alonzi
et al.
Article dans une revue
hal-03256952
v1
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Synthesis, Conformational Analysis, and Complexation Study of an Iminosugar-Aza-Crown, a Sweet Chiral Cyclam Analog
Alexandra Bordes
,
Ana Poveda
,
Thibault Troadec
,
Antonio Franconetti
,
Ana Arda
et al.
Article dans une revue
hal-02504835
v1
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Synthesis and glycosidase inhibition of conformationally locked DNJ and DMJ derivatives exploiting a 2-oxo- C -allyl iminosugar
Quentin Foucart
,
Yuna Shimadate
,
Jérôme Marrot
,
Atsushi Kato
,
Jérôme Désiré
et al.
Article dans une revue
hal-04418307
v1
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Site-Selective Debenzylation of C -Allyl Iminosugars Enables Their Stereocontroled Structure Diversification at the C-2 Position
Quentin Foucart
,
Jérôme Marrot
,
Jérôme Désiré
,
Yves Blériot
Article dans une revue
hal-04418300
v1
|
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Bi(OTf) 3 -mediated intramolecular epoxide opening for bicyclic azepane synthesis
Sha Zhu
,
Anh Tuan Tran
,
Yuki Hirokami
,
Geoffrey Gontard
,
Omar Khaled
et al.
Article dans une revue
hal-02181703
v1
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Lewis acid-catalysed nucleophilic opening of a bicyclic hemiaminal followed by ring contraction: Access to functionalized L-idonojirimycin derivatives
Nicolas Auberger
,
Benjamin Onfroy
,
Nathalie Fontelle
,
Quentin Foucart
,
Yves Bleriot
Article dans une revue
hal-02180492
v1
|
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2-Acetamido-2-deoxy- l -iminosugar C -Alkyl and C -Aryl Glycosides: Synthesis and Glycosidase Inhibition
Balkis Eddhif
,
Justin Lange
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Nadia Guignard
,
Yann Batonneau
,
Jonathan A. Clarhaut
et al.
Article dans une revue
hal-02172201
v1
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Catalyst-free synthesis of alkylpolyglycosides induced by high-frequency ultrasound
Prince Amaniampong
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Jean-Louis Clément
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Didier Gigmes
,
Carmen Ortiz Mellet
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José García fernández
et al.
Article dans une revue
hal-01937985
v1
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In silico analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay–Sachs disease
Atsushi Kato
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Izumi Nakagome
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Shinpei Nakagawa
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Kyoko Kinami
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Isao Adachi
et al.
Article dans une revue
hal-02176719
v1
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Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress β-lactam antibiotic resistance
Grishma Vadlamani
,
Keith A Stubbs
,
Jerome Desire
,
Yves Blériot
,
David J. Vocadlo
et al.
Article dans une revue
hal-02176780
v1
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Selective trihydroxylated azepane inhibitors of NagZ, a glycosidase involved in Pseudomonas aeruginosa resistance to β-lactam antibiotics
Jaufret Bouquet
,
Dustin King
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G. Vadlamani
,
G. Benzie
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Bogdan Iorga
et al.
Article dans une revue
hal-02176734
v1
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HF-Induced Intramolecular C -Arylation and C -Alkylation/Fluorination of 2-Aminoglycopyranoses
Nicolas Probst
,
Amélie Martin
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Jérôme Désiré
,
Agnès Mingot
,
Jerome Marrot
et al.
Article dans une revue
hal-01743477
v1
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Multivalency To Inhibit and Discriminate Hexosaminidases
Dimitri Alvarez-Dorta
,
Dustin King
,
Thibaut Legigan
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Daisuke Ide
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Isao Adachi
et al.
Article dans une revue
hal-01744683
v1
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Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens.
Marielle Tamigney Kenfack
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Marcelina Mazur
,
Teerapat Nualnoi
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Teresa L Shaffer
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Abba Ngassimou
et al.
Article dans une revue
pasteur-01574599
v1
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Catching elusive glycosyl cations in a condensed phase with HF/SbF₅ superacid
A. Martin
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A. Arda
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J. Désiré
,
A. Martin-Mingot
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N. Probst
et al.
Article dans une revue
hal-01505628
v1
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4'-Methoxyphenacyl-Assisted Synthesis of β-Kdo Glycosides
Marcelina Mazur
,
Barbara Barycza
,
Hanitra Andriamboavonjy
,
Serge Lavoie
,
Marielle Tamigney Kenfack
et al.
Article dans une revue
pasteur-01421190
v1
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Burkholderia pseudomallei Capsular Polysaccharide Recognition by a Monoclonal Antibody Reveals Key Details toward a Biodefense Vaccine and Diagnostics against Melioidosis
Roberta Marchetti
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Michael J. Dillon
,
Mary N. Burtnick
,
Mark A. Hubbard
,
Marielle Tamigney Kenfack
et al.
Article dans une revue
hal-01359499
v1
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Conformational Plasticity in Glycomimetics: Fluorocarbamethyl-L-idopyranosides Mimic the Intrinsic Dynamic Behaviour of Natural Idose Rings
Luca Unione
,
Bixue Xu
,
Dolores Diaz
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Sonsoles Martin-Santamaria
,
Ana Poveda
et al.
Article dans une revue
istex
hal-01366322
v1
|
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Synthetic deoxynojirimycin derivatives bearing a thiolated, fluorinated or unsaturated N-alkyl chain: identification of potent α-glucosidase and trehalase inhibitors as well as F508del-CFTR correctors.
V. Cendret
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T. Legigan
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A. Martin-Mingot
,
S. Thibaudeau
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I. Adachi
et al.
Article dans une revue
hal-01500682
v1
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Synthesis of pyrrolidine-based analogues of 2-acetamidosugars as N-acetyl glucosaminidase inhibitors
Anh Tuan Tran
,
Bo Luo
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Jagadeesh Yerri
,
Nicolas Auberger
,
Jérôme Désiré
et al.
Article dans une revue
hal-01136039
v1
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Synthesis of the Tetrasaccharide Repeating Unit of the β-Kdo-Containing Exopolysaccharide from Burkholderia pseudomallei and B. cepacia Complex.
A. Laroussarie
,
B. Barycza
,
H. Andriamboavonjy
,
M. Tamigney Kenfack
,
Y. Bleriot
et al.
Article dans une revue
hal-01501820
v1
|
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γ-Aminoalcohol rearrangement applied to pentahydroxylated azepanes provides pyrrolidines epimeric to homoDMDP
Y. Jagadeesh
,
A. Tran
,
B. Luo
,
N. Auberger
,
J. Désiré
et al.
Article dans une revue
hal-04543396
v1
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Site-selective hexa-hetero-functionalization of alpha-cyclodextrin an archetypical C-6-symmetric concave cycle
Bo Wang
,
Elena Zaborova
,
Samuel Guieu
,
Marta Petrillo
,
Maxime Guitet,
et al.
Article dans une revue
hal-01324074
v1
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Synthesis of 1,2-trans-2-Acetamido-2-deoxyhomoiminosugars
Yves Blériot
,
Anh Tuan Tran
,
Giuseppe Prencipe
,
Jagadeesh Yerri
,
Nicolas Auberger
et al.
Article dans une revue
hal-01315627
v1
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N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors
J. Désiré
,
M. Mondon
,
N. Fontelle
,
S. Nakagawa
,
Y. Hirokami
et al.
Article dans une revue
hal-01311606
v1
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gem-Difluorocarbadisaccharides: Restoring the exo-Anomeric Effect
R. Xu
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L. Unione
,
J. Sardinha
,
S. Wu
,
M. Etheve-Quelquejeu
et al.
Article dans une revue
istex
hal-01059984
v1
|
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Non-specific accumulation of glycosphingolipids in GNE myopathy
Katherine A. Patzel
,
Tal Yardeni
,
Erell Le Poëc-Celic
,
Petcharat Leoyklang
,
Heidi Dorward
et al.
Article dans une revue
hal-01707991
v1
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Synthesis of 1,2-cis-Homoiminosugars Derived from GlcNAc and GalNAc Exploiting a β-Amino Alcohol Skeletal Rearrangement
Yves Blériot
,
Nicolas Auberger
,
Jagadeesh Yerri
,
Charles Gauthier
,
Giuseppe Prencipe
et al.
Article dans une revue
hal-01315083
v1
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Conformational Selection in Glycomimetics: Human Galectin-1 Only Recognizes syn-Psi-Type Conformations of beta-1,3-Linked Lactose and Its C-Glycosyl Derivative
P. Vidal
,
V. Roldos
,
M. Fernandez-Alonso
,
B. Vauzeilles
,
Y. Blériot
et al.
Article dans une revue
istex
hal-00989845
v1
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Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to beta-lactams
M. Mondon
,
S. Hur
,
G. Vadlamani
,
Paulo Rodrigues
,
P. Tsybina
et al.
Article dans une revue
hal-00968733
v1
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C-branched iminosugars: α-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP compared to miglitol and miglustat.
Sarah F Jenkinson
,
Daniel Best
,
a Waldo Saville
,
James Mui
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R Fernando Martínez
et al.
Article dans une revue
hal-00990546
v1
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Skeletal rearrangement of seven-membered iminosugars: Synthesis of (−)-adenophorine, (−)-1-epi-adenophorine and derivatives and evaluation as glycosidase inhibitors
M. Mondon
,
Frédéric Lecornué
,
J. Guillard
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S. Nakagawa
,
A. Kato
et al.
Article dans une revue
istex
hal-00937553
v1
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Unexpected Double Bank Shot of Diisobutylaluminium Hydride for Triple Functionalisation of -Cyclodextrin
E. Zaborova
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M. Guitet
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G. Prencipe
,
Y. Blériot
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M. Ménand
et al.
Article dans une revue
hal-00949280
v1
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Novel imino sugar α-glucosidase inhibitors as antiviral drugs
J.D. Howe
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N. Smith
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L.J. Marvin
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N. Ardes-Guillot
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J. Désiré
et al.
Article dans une revue
istex
hal-00932306
v1
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Novel imino sugar α-glucosidase inhibitors as antiviral compounds.
J. D. Howe
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N. Smith
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M. J.-R. Lee
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N. Ardes-Guisot
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B. Vauzeilles
et al.
Article dans une revue
istex
hal-00856804
v1
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Towards a stable noeuromycin analog with a D-manno configuration: Synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes
J. Deschamp
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M. Mondon
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S. Nakagawa
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S. Kato
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D.S. Alonzi
et al.
Article dans une revue
istex
hal-00836749
v1
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Conformational analysis of seven-membered 1-N-iminosugars by NMR and molecular modelling
J. Pérez-Castells
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M. Fontanella
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A. Arda
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F.J. Canada
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M. Sollogoub
et al.
Article dans une revue
hal-00823367
v1
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Synthesis and conformational analysis of bicyclic mimics of alpha- and beta-D-glucopyranosides adopting the biologically relevant 2,5B conformation
L. Amorim
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Farias Marcelo
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J. Désiré
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M. Sollogoub
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J. Jimenez-Barbero
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Article dans une revue
istex
hal-00834859
v1
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Access to l- and d-Iminosugar C-Glycosides from a d-gluco-Derived 6-Azidolactol Exploiting a Ring Isomerization/Alkylation Strategy.
Martine Mondon
,
Nathalie Fontelle
,
Jérôme Désiré
,
Frédéric Lecornué
,
Jérôme Guillard
et al.
Article dans une revue
hal-00669930
v1
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Synthesis of gem-difluorocarbasugars by TIBAL induced rearrangement
J. Sardinha
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A.P. Rauter
,
M. Sollogoub
,
Y. Blériot
Carbohydrate Chemistry : Proven Methods, 2012, 2, (14), pp.129-135
Article dans une revue
hal-00912807
v1
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Synthesis of branched seven-membered 1-N-iminosugars and their evaluation as glycosidase inhibitors
H.Q. Li
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Y.M. Zhang
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S. Favre
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P. Vogel
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M. Sollogoub
et al.
Article dans une revue
istex
hal-00834946
v1
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Cyclodextrins selectively modified on both rims using an O-3-debenzylative post-functionalisation, a consequence of the Sorrento meeting
S. Guitet
,
S.A. de Beaumais
,
Y. Blériot
,
B. Vauzeilles
,
Y.M. Zhang
et al.
Article dans une revue
istex
hal-00824401
v1
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Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.
Nicolas Ardes-Guisot
,
Dominic S Alonzi
,
Gabriele Reinkensmeier
,
Terry D Butters
,
Caroline Norez
et al.
Article dans une revue
hal-00608881
v1
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Cavitand supported tetraphosphine: cyclodextrin offers a useful platform for Suzuki-Miyaura cross-coupling
E. Zaborova
,
J. Deschamp
,
S. Guieu
,
Y. Bleriot
,
G. Poli
et al.
Article dans une revue
hal-00705922
v1
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Cyclodextrin tetraplexes: first syntheses and potential as cross-linking agent
Thomas Lecourt
,
Y. Bleriot
,
R. Auzely-Velty
,
M. Sollogoub
Chemical Communications, 2010, pp.2238-2240
Article dans une revue
hal-00499335
v1
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Cystic fibrosis and diabetes: isoLAB and isoDAB, enantiomeric carbon-branched pyrrolidine iminosugars
Daniel Best
,
Sarah F Jenkinson
,
Waldo A. Saville
,
Dominic S Alonzi
,
Mark R Wormald
et al.
Article dans une revue
istex
hal-00580537
v1
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Duplex of capped-cyclodextrins, synthesis and cross-linking behaviour with a biopolymer
O. Bistri-Aslanoff
,
Y. Bleriot
,
R. Auzely-Velty
,
M. Sollogoub
Organic & Biomolecular Chemistry, 2010, pp.3437-3443
Article dans une revue
hal-00524349
v1
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Phenylenediamine catalysis of “click glycosylations” in water: practical and direct access to unprotected neoglycoconjugates
Aurélie Baron
,
Yves Blériot
,
Matthieu Sollogoub
,
Boris Vauzeilles
Article dans une revue
istex
hal-04388056
v1
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Looking forward : a glance into the future of organic chemistry
Philippe Compain
,
Valérie Desvergnes
,
Cyril Ollivier
,
Frédéric Robert
,
Franck Suzenet
et al.
Article dans une revue
istex
hal-00158370
v1
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Future alchemy: account of the ESYOP experiment
Philippe Compain
,
Valérie Desvergnes
,
Cyril Ollivier
,
Frédéric Robert
,
Franck Suzenet
et al.
Article dans une revue
istex
hal-00158010
v1
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