Yves Blériot

Full Professor - IC2MP - University of Poitiers

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yves-bleriot

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Publications

	Evaluation of nonnatural L-iminosugar C,C-glycosides, a new class of C-branched iminosugars, as glycosidase inhibitors Jérôme Désiré , Zakaria Debbah , David Gueyrard , Jérôme Marrot , Yves Blériot Carbohydrate Research, 2023, 532, pp.108903. ⟨10.1016/j.carres.2023.108903⟩ Journal articles hal-04542506v1
	Sugar-Derived Amidines and Congeners: Structures, Glycosidase Inhibition and Applications Yves Blériot , Nicolas Auberger , Jérôme Désiré Current Medicinal Chemistry, 2022, 29 (7), pp.1271-1292. ⟨10.2174/0929867329666211222164545⟩ Journal articles hal-04543430v1
	Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and C -alkylation leads to low micromolar HexAB and NagZ inhibitors J. Bouquet , N. Auberger , R. Ashmus , D. King , A. Bordes Organic & Biomolecular Chemistry, 2022, 20 (3), pp.619-629. ⟨10.1039/d1ob02280f⟩ Journal articles hal-04526197v1
	Stereoselective Synthesis of 1- C -Diethylphosphonomethyl and -difluoromethyl Iminosugars from Sugar Lactams Thanh Van Tran , Jérôme Désiré , Nicolas Auberger , Yves Blériot Journal of Organic Chemistry, 2022, 87 (11), pp.7581-7585. ⟨10.1021/acs.joc.2c00835⟩ Journal articles hal-03953681v1
	Synthesis, conformational analysis and glycosidase inhibition of bicyclic nojirimycin C-glycosides based on an octahydrofuro[3,2-b]pyridine motif Jérôme Désiré , Quentin Foucart , Ana Poveda , Gurvan Gourlaouen , Yuna Shimadate Carbohydrate Research, 2022, 511, pp.108491. ⟨10.1016/j.carres.2021.108491⟩ Journal articles hal-04542825v1
	Stereoselective Access to Iminosugar C, C-Glycosides from 6-Azidoketopyranoses Zakaria Debbah , Jérôme C. Marrot , Nicolas Auberger , Jérôme Désiré , Yves Blériot Organic Letters, 2022, 24 (25), pp.4542-4546. ⟨10.1021/acs.orglett.2c01560⟩ Journal articles hal-03775104v1
	Insight into the Ferrier rearrangement by combining flash chemistry and superacids Naresh Bhuma , Ludivine Lebedel , Hiroki Yamashita , Yutaka Shimizu , Zahra Abada Angewandte Chemie International Edition, 2021, 60 (4), pp.2036-2041. ⟨10.1002/anie.202010175⟩ Journal articles hal-03007376v1
	Contributing to the Study of Enzymatic and Chemical Glycosyl Transfer Through the Observation and Mimicry of Glycosyl Cations Yves Blériot Synthesis: Journal of Synthetic Organic Chemistry, 2021, 53 (05), pp.904-924. ⟨10.1055/s-0040-1706073⟩ Journal articles hal-04542796v1
	Iminosugar-C-glycosides work as pharmacological chaperones of NAGLU, a glycosidase involved in MPS IIIB rare disease Sha Zhu , Yerri Jagadeesh , Anh Tuan Tran , Alisdair Boraston , Dominic S Alonzi Chemistry - A European Journal, 2021, ⟨10.1002/chem.202101408⟩ Journal articles hal-03256952v1
	Synthesis and chelation study of a fluoroionophore and a glycopeptide based on an aza crown iminosugar structure Alexandra Bordes , Ana Poveda , Nathalie Fontelle , Ana Ardá , Jérôme Guillard Carbohydrate Research, 2021, 501, pp.108258. ⟨10.1016/j.carres.2021.108258⟩ Journal articles hal-04336072v1
	Glycosyl Oxocarbenium Ions: Structure, Conformation, Reactivity, and Interactions Antonio Franconetti , Ana Ardá , Juan Luis Asensio , Yves Blériot , Sébastien Thibaudeau Accounts of Chemical Research, 2021, 54 (11), pp.2552-2564. ⟨10.1021/acs.accounts.1c00021⟩ Journal articles hal-04542812v1
	Synthesis, Conformational Analysis, and Complexation Study of an Iminosugar-Aza-Crown, a Sweet Chiral Cyclam Analog Alexandra Bordes , Ana Poveda , Thibault Troadec , Antonio Franconetti , Ana Arda Organic Letters, 2020, 22 (6), pp.2344-2349. ⟨10.1021/acs.orglett.0c00503⟩ Journal articles hal-02504835v1
	Lewis acid-catalysed nucleophilic opening of a bicyclic hemiaminal followed by ring contraction: Access to functionalized L-idonojirimycin derivatives Nicolas Auberger , Benjamin Onfroy , Nathalie Fontelle , Quentin Foucart , Yves Bleriot Carbohydrate Research, 2019, 472, pp.65-71. ⟨10.1016/j.carres.2018.11.008⟩ Journal articles hal-02180492v1
	Bi(OTf) 3 -mediated intramolecular epoxide opening for bicyclic azepane synthesis Sha Zhu , Anh Tuan Tran , Yuki Hirokami , Geoffrey Gontard , Omar Khaled Journal of Carbohydrate Chemistry, 2019, 38 (2), pp.139-149. ⟨10.1080/07328303.2019.1581887⟩ Journal articles hal-02181703v1
	Site-Selective Debenzylation of C -Allyl Iminosugars Enables Their Stereocontroled Structure Diversification at the C-2 Position Quentin Foucart , Jérôme Marrot , Jérôme Désiré , Yves Blériot Organic Letters, 2019, 21 (12), pp.4821-4825. ⟨10.1021/acs.orglett.9b01712⟩ Journal articles hal-04418300v1
	Synthesis and glycosidase inhibition of conformationally locked DNJ and DMJ derivatives exploiting a 2-oxo- C -allyl iminosugar Quentin Foucart , Yuna Shimadate , Jérôme Marrot , Atsushi Kato , Jérôme Désiré Organic & Biomolecular Chemistry, 2019, 17 (30), pp.7204-7214. ⟨10.1039/c9ob01402k⟩ Journal articles hal-04418307v1
	Catalyst-free synthesis of alkylpolyglycosides induced by high-frequency ultrasound Prince Amaniampong , Jean-Louis Clément , Didier Gigmes , Carmen Ortiz Mellet , José García fernández ChemSusChem, 2018, 11 (16), pp.2673 - 2676. ⟨10.1002/cssc.201801137⟩ Journal articles hal-01937985v1
	2-Acetamido-2-deoxy- l -iminosugar C -Alkyl and C -Aryl Glycosides: Synthesis and Glycosidase Inhibition Balkis Eddhif , Justin Lange , Nadia Guignard , Yann Batonneau , Jonathan A. Clarhaut European Journal of Organic Chemistry, 2018, 2018 (40), pp.5477-5488. ⟨10.1002/ejoc.201800678⟩ Journal articles hal-02172201v1
	Multivalency To Inhibit and Discriminate Hexosaminidases Dimitri Alvarez-Dorta , Dustin King , Thibaut Legigan , Daisuke Ide , Isao Adachi Chemistry - A European Journal, 2017, 23 (38), pp.9022 - 9025. ⟨10.1002/chem.201701756⟩ Journal articles hal-01744683v1
	Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens. Marielle Tamigney Kenfack , Marcelina Mazur , Teerapat Nualnoi , Teresa L Shaffer , Abba Ngassimou Nature Communications, 2017, 8 (1), pp.115. ⟨10.1038/s41467-017-00173-8⟩ Journal articles pasteur-01574599v1
	Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress β-lactam antibiotic resistance Grishma Vadlamani , Keith A Stubbs , Jerome Desire , Yves Blériot , David J. Vocadlo Protein Science, 2017, 26 (6), pp.1161-1170. ⟨10.1002/pro.3166⟩ Journal articles hal-02176780v1
	Selective trihydroxylated azepane inhibitors of NagZ, a glycosidase involved in Pseudomonas aeruginosa resistance to β-lactam antibiotics Jaufret Bouquet , Dustin King , G. Vadlamani , G. Benzie , Bogdan Iorga Organic & Biomolecular Chemistry, 2017, 15 (21), pp.4609-4619. ⟨10.1039/C7OB00838D⟩ Journal articles hal-02176734v1
	HF-Induced Intramolecular C -Arylation and C -Alkylation/Fluorination of 2-Aminoglycopyranoses Nicolas Probst , Amélie Martin , Jérôme Désiré , Agnès Mingot , Jerome Marrot Organic Letters, 2017, 19 (5), pp.1040 - 1043. ⟨10.1021/acs.orglett.7b00003⟩ Journal articles hal-01743477v1
	In silico analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay–Sachs disease Atsushi Kato , Izumi Nakagome , Shinpei Nakagawa , Kyoko Kinami , Isao Adachi Organic & Biomolecular Chemistry, 2017, 15 (44), pp.9297-9304. ⟨10.1039/C7OB02281F⟩ Journal articles hal-02176719v1
	Catching elusive glycosyl cations in a condensed phase with HF/SbF₅ superacid A. Martin , A. Arda , J. Désiré , A. Martin-Mingot , N. Probst Nature Chemistry, 2016, ⟨10.1038/nchem.2399⟩ Journal articles hal-01505628v1
	4'-Methoxyphenacyl-Assisted Synthesis of β-Kdo Glycosides Marcelina Mazur , Barbara Barycza , Hanitra Andriamboavonjy , Serge Lavoie , Marielle Tamigney Kenfack Journal of Organic Chemistry, 2016, 81 (22), pp.10585-10599. ⟨10.1021/acs.joc.6b01431⟩ Journal articles pasteur-01421190v1
	γ-Aminoalcohol rearrangement applied to pentahydroxylated azepanes provides pyrrolidines epimeric to homoDMDP Y. Jagadeesh , A. Tran , B. Luo , N. Auberger , J. Désiré Organic & Biomolecular Chemistry, 2015, 13 (11), pp.3446-3456. ⟨10.1039/C5OB00050E⟩ Journal articles hal-04543396v1
	Synthesis of the Tetrasaccharide Repeating Unit of the β-Kdo-Containing Exopolysaccharide from Burkholderia pseudomallei and B. cepacia Complex. A. Laroussarie , B. Barycza , H. Andriamboavonjy , M. Tamigney Kenfack , Y. Bleriot Journal of Organic Chemistry, 2015, 80 (20), pp.10386-10396. ⟨10.1021/acs.joc.5b01823⟩ Journal articles hal-01501820v1
	Burkholderia pseudomallei Capsular Polysaccharide Recognition by a Monoclonal Antibody Reveals Key Details toward a Biodefense Vaccine and Diagnostics against Melioidosis Roberta Marchetti , Michael J. Dillon , Mary N. Burtnick , Mark A. Hubbard , Marielle Tamigney Kenfack ACS Chemical Biology, 2015, 10 pp.2295-2302. ⟨10.1021/acschembio.5b00502⟩ Journal articles hal-01359499v1
	Conformational Plasticity in Glycomimetics: Fluorocarbamethyl-L-idopyranosides Mimic the Intrinsic Dynamic Behaviour of Natural Idose Rings Luca Unione , Bixue Xu , Dolores Diaz , Sonsoles Martin-Santamaria , Ana Poveda Chemistry - A European Journal, 2015, 21 pp.10513-10521. ⟨10.1002/chem.201501249⟩ Journal articles hal-01366322v1
	Synthesis of pyrrolidine-based analogues of 2-acetamidosugars as N-acetyl glucosaminidase inhibitors Anh Tuan Tran , Bo Luo , Jagadeesh Yerri , Nicolas Auberger , Jérôme Désiré Carbohydrate Research, 2015, 409, pp.56-62. ⟨10.1016/j.carres.2015.02.014⟩ Journal articles hal-01136039v1
	Synthetic deoxynojirimycin derivatives bearing a thiolated, fluorinated or unsaturated N-alkyl chain: identification of potent α-glucosidase and trehalase inhibitors as well as F508del-CFTR correctors. V. Cendret , T. Legigan , A. Martin-Mingot , S. Thibaudeau , I. Adachi Organic & Biomolecular Chemistry, 2015, 13 (43), pp.10734-10744. ⟨10.1039/c5ob01526j⟩ Journal articles hal-01500682v1
	Synthesis of 1,2-trans-2-Acetamido-2-deoxyhomoiminosugars Yves Blériot , Anh Tuan Tran , Giuseppe Prencipe , Jagadeesh Yerri , Nicolas Auberger Organic Letters, 2014, 16 (21 ), pp.5516-5519. ⟨10.1021/ol502929h⟩ Journal articles hal-01315627v1
	Non-specific accumulation of glycosphingolipids in GNE myopathy Katherine A. Patzel , Tal Yardeni , Erell Le Poëc-Celic , Petcharat Leoyklang , Heidi Dorward Journal of Inherited Metabolic Disease, 2014, 37 (2), pp.297--308. ⟨10.1007/s10545-013-9655-6⟩ Journal articles hal-01707991v1
	gem-Difluorocarbadisaccharides: Restoring the exo-Anomeric Effect R. Xu , L. Unione , J. Sardinha , S. Wu , M. Etheve-Quelquejeu Angewandte Chemie International Edition, 2014, 53, pp.9597 -9602. ⟨10.1002/anie.201405008⟩ Journal articles hal-01059984v1
	Synthesis of 1,2-cis-Homoiminosugars Derived from GlcNAc and GalNAc Exploiting a β-Amino Alcohol Skeletal Rearrangement Yves Blériot , Nicolas Auberger , Jagadeesh Yerri , Charles Gauthier , Giuseppe Prencipe Organic Letters, 2014, 16 (21 ), pp.5512-5515. ⟨10.1021/ol502926f⟩ Journal articles hal-01315083v1
	Site-selective hexa-hetero-functionalization of alpha-cyclodextrin an archetypical C-6-symmetric concave cycle Bo Wang , Elena Zaborova , Samuel Guieu , Marta Petrillo , Maxime Guitet, Nature Communications, 2014, 5, pp.5354. ⟨10.1038/ncomms6354⟩ Journal articles hal-01324074v1
	N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors J. Désiré , M. Mondon , N. Fontelle , S. Nakagawa , Y. Hirokami Organic & Biomolecular Chemistry, 2014, 12 (44), pp.8977-8996. ⟨10.1039/c4ob00325j⟩ Journal articles hal-01311606v1
	Novel imino sugar α-glucosidase inhibitors as antiviral compounds. J. D. Howe , N. Smith , M. J.-R. Lee , N. Ardes-Guisot , B. Vauzeilles Bioorganic and Medicinal Chemistry, 2013, 21 (16), pp.4831-8. ⟨10.1016/j.bmc.2013.03.014⟩ Journal articles hal-00856804v1
	Skeletal rearrangement of seven-membered iminosugars: Synthesis of (−)-adenophorine, (−)-1-epi-adenophorine and derivatives and evaluation as glycosidase inhibitors M. Mondon , Frédéric Lecornué , J. Guillard , S. Nakagawa , A. Kato Bioorganic and Medicinal Chemistry, 2013, 21 (16), pp.4803-4812. ⟨10.1016/j.bmc.2013.03.035⟩ Journal articles hal-00937553v1
	Unexpected Double Bank Shot of Diisobutylaluminium Hydride for Triple Functionalisation of -Cyclodextrin E. Zaborova , M. Guitet , G. Prencipe , Y. Blériot , M. Ménand Angewandte Chemie International Edition, 2013, 52, pp.639-644 Journal articles hal-00949280v1
	Novel imino sugar α-glucosidase inhibitors as antiviral drugs J.D. Howe , N. Smith , L.J. Marvin , N. Ardes-Guillot , J. Désiré Bioorganic and Medicinal Chemistry, 2013, 21, pp.4831-4838. ⟨10.1016/j.bmc.2013.03.014⟩ Journal articles hal-00932306v1
	Conformational Selection in Glycomimetics: Human Galectin-1 Only Recognizes syn-Psi-Type Conformations of beta-1,3-Linked Lactose and Its C-Glycosyl Derivative P. Vidal , V. Roldos , M. Fernandez-Alonso , B. Vauzeilles , Y. Blériot Chemistry - A European Journal, 2013, 19 (43), pp.14581-14590. ⟨10.1002/chem.201301244⟩ Journal articles hal-00989845v1
	Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to beta-lactams M. Mondon , S. Hur , G. Vadlamani , Paulo Rodrigues , P. Tsybina Chemical Communications, 2013, 49 (93), pp.10983-10985. ⟨10.1039/c3cc46646a⟩ Journal articles hal-00968733v1
	C-branched iminosugars: α-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP compared to miglitol and miglustat. Sarah F Jenkinson , Daniel Best , a Waldo Saville , James Mui , R Fernando Martínez Journal of Organic Chemistry, 2013, 78 (15), pp.7380-97. ⟨10.1021/jo4005487⟩ Journal articles hal-00990546v1
	Cyclodextrins selectively modified on both rims using an O-3-debenzylative post-functionalisation, a consequence of the Sorrento meeting S. Guitet , S.A. de Beaumais , Y. Blériot , B. Vauzeilles , Y.M. Zhang Carbohydrate Research, 2012, 356, pp.278-281. ⟨10.1016/j.carres.2011.12.002⟩ Journal articles hal-00824401v1
	Conformational analysis of seven-membered 1-N-iminosugars by NMR and molecular modelling J. Pérez-Castells , M. Fontanella , A. Arda , F.J. Canada , M. Sollogoub New Journal of Chemistry, 2012, 36 (4), pp.1008-1013. ⟨10.1039/c2nj20967e⟩ Journal articles hal-00823367v1
	Synthesis and conformational analysis of bicyclic mimics of alpha- and beta-D-glucopyranosides adopting the biologically relevant 2,5B conformation L. Amorim , Farias Marcelo , J. Désiré , M. Sollogoub , J. Jimenez-Barbero Carbohydrate Research, 2012, 361, pp.219-224. ⟨10.1016/j.carres.2012.07.005⟩ Journal articles hal-00834859v1
	Access to l- and d-Iminosugar C-Glycosides from a d-gluco-Derived 6-Azidolactol Exploiting a Ring Isomerization/Alkylation Strategy. Martine Mondon , Nathalie Fontelle , Jérôme Désiré , Frédéric Lecornué , Jérôme Guillard Organic Letters, 2012, 14 (3), pp.870-3. ⟨10.1021/ol203385w⟩ Journal articles hal-00669930v1
	Synthesis of gem-difluorocarbasugars by TIBAL induced rearrangement J. Sardinha , A.P. Rauter , M. Sollogoub , Y. Blériot Carbohydrate Chemistry : Proven Methods, 2012, 2, (14), pp.129-135 Journal articles hal-00912807v1
	Synthesis of branched seven-membered 1-N-iminosugars and their evaluation as glycosidase inhibitors H.Q. Li , Y.M. Zhang , S. Favre , P. Vogel , M. Sollogoub Carbohydrate Research, 2012, 356, pp.110-114. ⟨10.1016/j.carres.2011.10.039⟩ Journal articles hal-00834946v1
	Towards a stable noeuromycin analog with a D-manno configuration: Synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes J. Deschamp , M. Mondon , S. Nakagawa , S. Kato , D.S. Alonzi Bioorganic and Medicinal Chemistry, 2012, 20 (2), pp.641-649. ⟨10.1016/j.bmc.2010.09.053⟩ Journal articles hal-00836749v1
	Cavitand supported tetraphosphine: cyclodextrin offers a useful platform for Suzuki-Miyaura cross-coupling E. Zaborova , J. Deschamp , S. Guieu , Y. Bleriot , G. Poli Chemical Communications, 2011, 47 (32), pp.9206-9208. ⟨10.1039/c1cc12241j⟩ Journal articles hal-00705922v1
	Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain. Nicolas Ardes-Guisot , Dominic S Alonzi , Gabriele Reinkensmeier , Terry D Butters , Caroline Norez Organic & Biomolecular Chemistry, 2011, 9 (15), pp.5373-5388. ⟨10.1039/c1ob05119a⟩ Journal articles hal-00608881v1
	Cyclodextrin tetraplexes: first syntheses and potential as cross-linking agent Thomas Lecourt , Y. Bleriot , R. Auzely-Velty , M. Sollogoub Chemical Communications, 2010, pp.2238-2240 Journal articles hal-00499335v1
	Cystic fibrosis and diabetes: isoLAB and isoDAB, enantiomeric carbon-branched pyrrolidine iminosugars Daniel Best , Sarah F Jenkinson , Waldo A. Saville , Dominic S Alonzi , Mark R Wormald Tetrahedron Letters, 2010, 51 (32), pp.4170-4174. ⟨10.1016/j.tetlet.2010.05.131⟩ Journal articles hal-00580537v1
	Duplex of capped-cyclodextrins, synthesis and cross-linking behaviour with a biopolymer O. Bistri-Aslanoff , Y. Bleriot , R. Auzely-Velty , M. Sollogoub Organic & Biomolecular Chemistry, 2010, pp.3437-3443 Journal articles hal-00524349v1
	Phenylenediamine catalysis of “click glycosylations” in water: practical and direct access to unprotected neoglycoconjugates Aurélie Baron , Yves Blériot , Matthieu Sollogoub , Boris Vauzeilles Organic & Biomolecular Chemistry, 2008, 6 (11), pp.1898. ⟨10.1039/B805528A⟩ Journal articles hal-04388056v1
	Future alchemy: account of the ESYOP experiment Philippe Compain , Valérie Desvergnes , Cyril Ollivier , Frédéric Robert , Franck Suzenet Comptes Rendus. Chimie, 2006, 9, pp.127-140. ⟨10.1016/j.crci.2005.09.004⟩ Journal articles hal-00158010v1
	Looking forward : a glance into the future of organic chemistry Philippe Compain , Valérie Desvergnes , Cyril Ollivier , Frédéric Robert , Franck Suzenet New Journal of Chemistry, 2006, 30 (6), pp.823-831. ⟨10.1039/B601837H⟩ Journal articles hal-00158370v1

	High ultrasonic frequencies for selective oxidation of sugars: new investigations and insights Gregory Chatel , Prince Amaniampong , Ayman Karam , Carmen Ortiz Mellet , José Garcia Fernandez 16th Meeting of the European Society of Sonochemistry, Apr 2018, Besançon, France Conference papers hal-01940086v1

Yves Blériot

Publications

Evaluation of nonnatural L-iminosugar C,C-glycosides, a new class of C-branched iminosugars, as glycosidase inhibitors

Sugar-Derived Amidines and Congeners: Structures, Glycosidase Inhibition and Applications

Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and C -alkylation leads to low micromolar HexAB and NagZ inhibitors

Stereoselective Synthesis of 1- C -Diethylphosphonomethyl and -difluoromethyl Iminosugars from Sugar Lactams

Synthesis, conformational analysis and glycosidase inhibition of bicyclic nojirimycin C-glycosides based on an octahydrofuro[3,2-b]pyridine motif

Stereoselective Access to Iminosugar C, C-Glycosides from 6-Azidoketopyranoses

Insight into the Ferrier rearrangement by combining flash chemistry and superacids

Contributing to the Study of Enzymatic and Chemical Glycosyl Transfer Through the Observation and Mimicry of Glycosyl Cations

Iminosugar-C-glycosides work as pharmacological chaperones of NAGLU, a glycosidase involved in MPS IIIB rare disease

Synthesis and chelation study of a fluoroionophore and a glycopeptide based on an aza crown iminosugar structure

Glycosyl Oxocarbenium Ions: Structure, Conformation, Reactivity, and Interactions

Synthesis, Conformational Analysis, and Complexation Study of an Iminosugar-Aza-Crown, a Sweet Chiral Cyclam Analog

Lewis acid-catalysed nucleophilic opening of a bicyclic hemiaminal followed by ring contraction: Access to functionalized L-idonojirimycin derivatives

Bi(OTf) 3 -mediated intramolecular epoxide opening for bicyclic azepane synthesis

Site-Selective Debenzylation of C -Allyl Iminosugars Enables Their Stereocontroled Structure Diversification at the C-2 Position

Synthesis and glycosidase inhibition of conformationally locked DNJ and DMJ derivatives exploiting a 2-oxo- C -allyl iminosugar

Catalyst-free synthesis of alkylpolyglycosides induced by high-frequency ultrasound

2-Acetamido-2-deoxy- l -iminosugar C -Alkyl and C -Aryl Glycosides: Synthesis and Glycosidase Inhibition

Multivalency To Inhibit and Discriminate Hexosaminidases

Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens.

Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress β-lactam antibiotic resistance

Selective trihydroxylated azepane inhibitors of NagZ, a glycosidase involved in Pseudomonas aeruginosa resistance to β-lactam antibiotics

HF-Induced Intramolecular C -Arylation and C -Alkylation/Fluorination of 2-Aminoglycopyranoses

In silico analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay–Sachs disease

Catching elusive glycosyl cations in a condensed phase with HF/SbF₅ superacid

4'-Methoxyphenacyl-Assisted Synthesis of β-Kdo Glycosides

γ-Aminoalcohol rearrangement applied to pentahydroxylated azepanes provides pyrrolidines epimeric to homoDMDP

Synthesis of the Tetrasaccharide Repeating Unit of the β-Kdo-Containing Exopolysaccharide from Burkholderia pseudomallei and B. cepacia Complex.

Burkholderia pseudomallei Capsular Polysaccharide Recognition by a Monoclonal Antibody Reveals Key Details toward a Biodefense Vaccine and Diagnostics against Melioidosis

Conformational Plasticity in Glycomimetics: Fluorocarbamethyl-L-idopyranosides Mimic the Intrinsic Dynamic Behaviour of Natural Idose Rings

Synthesis of pyrrolidine-based analogues of 2-acetamidosugars as N-acetyl glucosaminidase inhibitors

Synthetic deoxynojirimycin derivatives bearing a thiolated, fluorinated or unsaturated N-alkyl chain: identification of potent α-glucosidase and trehalase inhibitors as well as F508del-CFTR correctors.

Synthesis of 1,2-trans-2-Acetamido-2-deoxyhomoiminosugars

Non-specific accumulation of glycosphingolipids in GNE myopathy

gem-Difluorocarbadisaccharides: Restoring the exo-Anomeric Effect

Synthesis of 1,2-cis-Homoiminosugars Derived from GlcNAc and GalNAc Exploiting a β-Amino Alcohol Skeletal Rearrangement

Site-selective hexa-hetero-functionalization of alpha-cyclodextrin an archetypical C-6-symmetric concave cycle

N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors

Novel imino sugar α-glucosidase inhibitors as antiviral compounds.

Skeletal rearrangement of seven-membered iminosugars: Synthesis of (−)-adenophorine, (−)-1-epi-adenophorine and derivatives and evaluation as glycosidase inhibitors

Unexpected Double Bank Shot of Diisobutylaluminium Hydride for Triple Functionalisation of -Cyclodextrin

Novel imino sugar α-glucosidase inhibitors as antiviral drugs

Conformational Selection in Glycomimetics: Human Galectin-1 Only Recognizes syn-Psi-Type Conformations of beta-1,3-Linked Lactose and Its C-Glycosyl Derivative

Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to beta-lactams

C-branched iminosugars: α-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP compared to miglitol and miglustat.

Cyclodextrins selectively modified on both rims using an O-3-debenzylative post-functionalisation, a consequence of the Sorrento meeting

Conformational analysis of seven-membered 1-N-iminosugars by NMR and molecular modelling

Synthesis and conformational analysis of bicyclic mimics of alpha- and beta-D-glucopyranosides adopting the biologically relevant 2,5B conformation

Access to l- and d-Iminosugar C-Glycosides from a d-gluco-Derived 6-Azidolactol Exploiting a Ring Isomerization/Alkylation Strategy.

Synthesis of gem-difluorocarbasugars by TIBAL induced rearrangement

Synthesis of branched seven-membered 1-N-iminosugars and their evaluation as glycosidase inhibitors

Towards a stable noeuromycin analog with a D-manno configuration: Synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes

Cavitand supported tetraphosphine: cyclodextrin offers a useful platform for Suzuki-Miyaura cross-coupling

Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.

Cyclodextrin tetraplexes: first syntheses and potential as cross-linking agent

Cystic fibrosis and diabetes: isoLAB and isoDAB, enantiomeric carbon-branched pyrrolidine iminosugars

Duplex of capped-cyclodextrins, synthesis and cross-linking behaviour with a biopolymer

Phenylenediamine catalysis of “click glycosylations” in water: practical and direct access to unprotected neoglycoconjugates

Future alchemy: account of the ESYOP experiment

Looking forward : a glance into the future of organic chemistry

High ultrasonic frequencies for selective oxidation of sugars: new investigations and insights